Document Category: Dermatology

EVects of hyperbaric oxygen on expression of Ž brinolytic factors of human endothelium in a simulated ischaemia/reperfusion situation

treating disorders other than decompression sickness. Still, HBO2is a treatmentmodality that has gained recognition in certain situations of ischaemia reper fusion. However, not much is known about its eVect on the endothelial cells.Based on earlier studies, the hypothesis was that HBO2treatment stimulates therelease of Ž brinolytic factors. The aim of the study was to investigate …

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Livedoid vasculopathy: long-term follow-up results following hyperbaric oxygen therapy

Background Livedoid vasculopathy, also known as atrophie blanche, is a recurrentpainful vasculopathy appearing mostly on the lower limbs. Treatment is challeng ing and relapses are frequent.Objectives To analyse the long-term effect and safety of hyperbaric oxygen (HBO)therapy in treating livedoid vasculopathy.Methods Twelve patients with active livedoid vasculopathy were included in thisstudy. All patients underwent HBO …

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Hyperbaric oxygen therapy for nonhealing vasculitic ulcers

Background. Cutaneous nonhealing ulceration is a threatening manifestation ofvasculitis. Hyperbaric oxygen (HBO), frequently used as adjuvant therapy for patientswith ischaemic ulcers, exerts additional beneficial effects on the vascular inflammatoryresponse.Aim. To evaluate the effect of HBO on vasculitis-induced nonhealing skin ulcers.Methods. The study population comprised 35 patients aged ‡ 18 years with severe,nonhealing, vasculitis-induced ulcers that …

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Hyperbaric oxygen therapy for chronic radiation-induced tissue injuries: Australasia’s largest study

AbstractAim: Chronic radiation injuries, although uncommon, are associated with poor quality of life in oncology patients. The present study assesses the efficacy and safety of hyperbaric oxygen therapy in the management of chronic radiation-induced tissue injuries.Methods: A retrospective analysis was performed in 276 consecutive patients treated with hyperbaric oxygen therapy for chronic radiation-induced tissue injuries …

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Hyperbaric oxygen therapy in the treatment of radio-induced lesions in normal tissues: a literature review

AbstractLate complications are one of the major factors limiting radiotherapy treatment, and their treatment is not codified. Hyperbaric oxygen(HBO) has been used in combination with radiotherapy for over half a century, either to maximise its effectiveness or in an attempt to treatlate complications. In this latter case, retrospective trials and case reports are prevailing in …

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TRATAMIENTO CON OXIGENACIÓN HIPERBÁRICA EN ONCOLOGÍA

ResumenLa terapia de oxigenación hiperbárica (TOHB) combate la hipoxia, factor predisponente para la resistencia a terapias oncológicas convencionales. Su uso como sensibilizador en terapias convencionales ha demostrado aumentar la efectividad de la radioterapia y disminuir la mortalidad en algunos tumores de cabeza y cuello y existe amplia evidencia de su uso en las lesiones radioinducidas. Más aún, …

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Deep Frostbite Treated With Hyperbaric Oxygen and Thrombolytic Therapies

Abstract: The authors present a case of deep frostbite treated with both hyperbaric oxygen and thrombolytic therapies. Both of these therapies are experimental and have not yet achieved widespread clinical use. The patient described in this paper sustained frostbite after becoming intoxicated and falling unconscious in a snowy field. He was treated acutely for hypothermia and came into the authors’ care …

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Hyperbaric oxygen – its mechanisms and efficacy

Background:This paper outlines therapeutic mechanisms of hyperbaric oxygen therapy (HBO2) and reviews data on its efficacy for clinical problems seen by plastic and reconstructive surgeons.Methods: The information in this review was obtained from the peer-reviewed medical literature.Results: Principal mechanisms of HBO2 are based on intracellular generation of reactive species of oxygen and nitrogen. Reactive species …

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