Document Category: Sports

The National Brain Injury, Rescue and Rehabilitation Study – a multicenter observational study of hyperbaric oxygen for mild traumatic brain injury with post-concussive symptoms

The National Brain Injury Rescue and Rehabilitation Project was established as a preliminary study to test the safety and practicality of multi-center hyperbaric oxygen administration for the post-concussive symptoms of chronic mild traumatic brain injury as a precursor to a pivotal, independent, multi-center, controlled clinical trial. This report presents the results for 32 subjects who …

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Case control study: hyperbaric oxygen treatment of mild traumatic brain injury persistent post-concussion syndrome and post-traumatic stress disorder

Mild traumatic brain injury (TBI) persistent post-concussion syndrome (PPCS) and post-traumatic stress disorder (PTSD) are epi demic in United States Iraq and Afghanistan War veterans. Treatment of the combined diagnoses is limited. The aim of this study is to assess safety, feasibility, and effectiveness of hyperbaric oxygen treatments (HBOT) for mild TBI PPCS and PTSD. …

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Hyperbaric oxygen therapy for traumatic brain injury: bench-to-bedside

Traumatic brain injury (TBI) is a serious public health problem in the United States. Survivors of TBI are often left with significant cognitive, behavioral, and communicative disabilities. So far there is no effective treatment/intervention in the daily clinical practice for TBI patients. The protective effects of hyperbaric oxygen therapy (HBOT) have been proved in stroke; however, its …

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Hyperbaric Oxygen Therapy Can Improve Post Concussion Syndrome Years after Mild Traumatic Brain Injury – Randomized Prospective Trial

AbstractBackground: Traumatic brain injury (TBI) is the leading cause of death and disability in the US. Approximately 70-90% of theTBI cases are classified as mild, and up to 25% of them will not recover and suffer chronic neurocognitive impairments. Themain pathology in these cases involves diffuse brain injuries, which are hard to detect by anatomical …

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A Phase I Study of Low-Pressure Hyperbaric Oxygen Therapy for Blast-Induced Post-Concussion Syndrome and Post-Traumatic Stress Disorder

AbstractThis is a preliminary report on the safety and efficacy of 1.5 ATA hyperbaric oxygen therapy (HBOT) in militarysubjects with chronic blast-induced mild to moderate traumatic brain injury (TBI)/post-concussion syndrome(PCS) and post-traumatic stress disorder (PTSD). Sixteen military subjects received 40 1.5 ATA/60 min HBOTsessions in 30 days. Symptoms, physical and neurological exams, SPECT brain imaging, …

A Phase I Study of Low-Pressure Hyperbaric Oxygen Therapy for Blast-Induced Post-Concussion Syndrome and Post-Traumatic Stress Disorder Read More »

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Hyperbaric Oxygen Therapy in Sports Musculoskeletal Injuries

Abstract  Hyperbaric oxygen therapy (HBOT) is a well-established treatment for a variety of conditions. HBOT is the administration of 100% oxygen breathing in a pressure vessel at higher than atmospheric pressure (1 atmosphere absolute = 101 kPa). Typically, treatment is given daily for between one and two hours at pressures of 2.0 to 2.8 ATA, depending …

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Hyperbaric oxygen reduces infammation, oxygenates injured muscle, and regenerates skeletal muscle via macrophage and satellite cell activation

Hyperbaric oxygen treatment (HBO) promotes rapid recovery from soft tissue injuries. However, the healing mechanism is unclear. Here we assessed the efects of HBO on contused calf muscles in a rat skeletal muscle injury model. An experimental HBO chamber was developed and rats were treated with 100% oxygen, 2.5 atmospheres absolute for 2h/day after injury. …

Hyperbaric oxygen reduces infammation, oxygenates injured muscle, and regenerates skeletal muscle via macrophage and satellite cell activation Read More »

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Effects of Hyperbaric Oxygen at 1.25 Atmospheres Absolute with Normal Air on Macrophage Number and Infiltration during Rat Skeletal Muscle Regeneration

Use of mild hyperbaric oxygen less than 2 atmospheres absolute (2026.54 hPa)with normal air is emerging as a common complementary treatment for severemuscle injury. Although hyperbaric oxygen at over 2 atmospheres absolute with100% O2 promotes healing of skeletal muscle injury, it is not clear whether mildhyperbaric oxygen is equally effective. The purpose of the present …

Effects of Hyperbaric Oxygen at 1.25 Atmospheres Absolute with Normal Air on Macrophage Number and Infiltration during Rat Skeletal Muscle Regeneration Read More »

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Effects of hyperbaric oxygen on gene expressions of procollagen, matrix metalloproteinase and tissue inhibitor of metalloproteinase in injured medial collateral ligament and anterior cruciate ligament

Abstract Animal experiments were performed toinvestigate whether and how the administration ofhyperbaric oxygen (HBO) affects gene expressions ofprocollagens, matrix metalloproteinases (MMPs) andtissue inhibitors of metalloproteinases (TIMPs) in in jured medial collateral ligament (MCL) and anteriorcruciate ligament (ACL). In 64 Sprague-Dawley rats,the MCL of the left knee was lacerated at the mid substance, and the ACL …

Effects of hyperbaric oxygen on gene expressions of procollagen, matrix metalloproteinase and tissue inhibitor of metalloproteinase in injured medial collateral ligament and anterior cruciate ligament Read More »

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