Document Category: Cardiology

Hyperbaric Oxygen Intervention Modulates Early Brain Injury after Experimental Subarachnoid Hemorrhage in Rats: Possible Involvement of TLR4/NF-κ B-Mediated Signaling Pathway

Background/Aims: Previous studies have proved that the activation of TLR4/NF-κ B signaling pathway is involved in inflammatory processes in early brain injury (EBI) after subarachnoid hemorrhage (SAH). Hyperbaric oxygen (HBO) intervention has successfully been used to treat several animal models of tissue injury via its anti-inflammation property. This study was undertaken to investigate the influence …

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An overview of protective strategies against ischemia/reperfusion injury: The role of hyperbaric oxygen preconditioning

Introduction: Ischemia/reperfusion (I/R) injury, such as myocardial infarction, stroke, and peripheral vascular disease, has been recognized as the most frequent causes of devastating disorders and death currently. Protective effect of various preconditioning stimuli, including hyperbaric oxygen (HBO), has been proposed in the management of I/R. Methods: In this study, we searched and reviewed up-to-date published …

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The role of hyperbaric oxygen therapy in the treatment of sternal wound infection

SummarySternal wound dehiscence and infection are major problems for patients and health care providers. A range of risk factors, including diabetes, obesity and internal thoracic artery harvest, has been implicated. Several pathophysiological mechanisms, which may account for the development of infection, have been proposed. There is a growing body of evidence which suggests that sternal …

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Hyperbaric oxygen therapy as additional treatment in deep sternal wound infections – a single center’s experience

AbstractIntroduction: Deep sternal wound infection (DSWI) is one of the most serious complications after cardiac surgery proce dures, observed in 5% of patients. Current standard medical therapy for DSWI includes antibiotics, surgical debridement, resuturing or negative pressure wound therapy (NPWT). Un fortunately, in some cases these methods are insufficient, and additional therapeutic options are needed. Aim: To …

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Role of Hyperbaric Oxygen Therapy in the Treatment of Postoperative Organ/Space Sternal Surgical Site Infections

AbstractBackground A prospective trial was designed to evaluatethe effect of hyperbaric oxygen (HBO) therapy on organ/space sternal surgical site infections (SSIs) following car diac surgery that requires sternotomy.Methods A total of 32 patients who developed postop erative organ/space sternal SSI were enrolled in this study from 1999 through 2005. All patients were offered HBOtherapy. Group …

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Different oxygen treatment pressures alter inflammatory gene expression in human endothelial cells

Hyperbaric oxygen has proven to be a useful treatment for chronic wounds. However, therapeutic conditions vary between treatment centers, and we wished to investigate the effects of different treatment pressures on cells under inflammatory conditions. Endothelial cells were exposed to a chronic wound model com prising hypoxia (2% O2 at 1 atmosphere absolute (atm abs); PO2 …

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Effects of hyperbaric oxygen on vascular endothelial function in patients with slow coronary flow

AbstractBackground: To improve therapy for slow coronary flow (SCF), the effects of hyperbaric oxygen (HBO) therapy on vascular endothelial function in SCF patients is the focus of this investigation. Methods: Ninety-eight patients who exhibited chest discomfort were retrospectively analyzed, and di agnosed with SCF by coronary artery angiography at the Third Hospital of Hebei Medical University, Shijiazhuang, …

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Hyperbaric oxygen therapy reduces the risk of QTc interval prolongation in patients with diabetes and hard-to-heal foot ulcers

Aims: Heart rate corrected QT (QTc) interval prolongation is a risk factor associated with increased mortality.Hyperbaric oxygen therapy (HBO) has previously been shown to have acute beneficial effects on QTc dispersion. The aim of this study was to evaluate long-term effects of HBO on QTc time in diabetic patients with hard-to-heal foot ulcers.Methods: In a …

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Hyperbaric oxygen therapy for acute coronary syndrome

BackgroundAcute coronary syndrome (ACS), includes acute myocardial infarction and unstable angina, is common and may prove fatal. Hyperbaricoxygen therapy (HBOT) will improve oxygen supply to the threatened heart and may reduce the volume of heart muscle that perishes.The addition of HBOT to standard treatment may reduce death rate and other major adverse outcomes.This an update …

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Cardiorespiratory alterations in patients undergoing hyperbaric oxygen therapy

Objective: To evaluate cardiorespiratory alterations due to a single session of hyperbaricoxygen therapy. Method: Randomized study with patients: a control group and hyperbaricoxygen therapy. Evaluations occurred in the beginning, during, and after exposureto pure oxygen above atmosphere for 2 hours. Systemic blood pressure, peripheraloxygen saturation, pulse rate, lung volume and lung capacity, and maximal inspiratoryand …

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