Document Category: Dermatology

Background: Snakebites are a neglected threat to global human health with a high morbidity rate. The present study explored the efficacy of antivenom with hyperbaric oxygen (HBO) intervention on snakebites, which could provide the experimental basis for clinical adjuvant therapy.Methods: Male Sprague–Dawley rats (n = 96) were randomized into four groups: the poison model was …

Increased Efficacy of Antivenom Combined with Hyperbaric Oxygen on Deinagkistrodon acutus Envenomation in Adult Rats Read More »

A patient suffered from an envenomation that, at his hospitalization, was judged severe: Grade 3 out of 3, as defined in clinical studies for CroFab™ antidote [Crotalidae Polyvalent Immune Fab (Ovine)]. In addition to the usual antivenom treatment we applied adjunctive hyperbaric oxygen (HBO2) therapy. Our aim was to facilitate better control of the lesions, already presenting as problematic wounds and …

HBO2 in snake envenomation (atrox albinus rattlesnake): a case report in a human Read More »

ABSTRACTAim: Snakebite injuries are common in tropical India among those who are involved in outdoor activities. These injuries results in cellulitis, gangrene at the bite area, bleeding manifestations, compartment syndrome, regional lymphadenopathy, septicemia, hypotension, and disseminated intravascular coagulation (DIC) resulting in significant morbidity and mortality. The purpose of this study is to share our experience of …

A Multidisciplinary Approach with Hyperbaric Oxygen Therapy Improve Outcome in Snake Bite Injuries Read More »

AbstractEvery year 10 to 20 cases of snake bites are reported on the Caribbean island of Martinique. The only snake involved, Bothrops lanceolatus, is endemic on the island, and its bite may lead to systemic multifocal thrombotic complications in the absence of the monospecific antivenom. Between January 1988 and January 2009, more than 250 snake bites have been …

Hyperbaric oxygen therapy after Bothrops lanceolatus snake bites in Martinique: A brief report Read More »

Loxosceles reclusa (L.reclusa) is known to bite humans, and its venom includes several enzymes that cause clinical symptoms. Loxoscelism, a condition due to being bitten by Loxosceles spiders, commonly known as recluses, can involve a range of clinical conditions, from local cutaneous lesions to severe systemic involvement. The diagnosis of loxoscelism is usually made by anamnesis and clinical findings. Magnetic resonance imaging is …

A loxoscelism case received therapeutic apheresis and hyperbaric oxygen therapy Read More »

ABSTRACTBACKGROUND: Bites by Loxosceles spiders (also known asrecluse spiders or brown spiders) can cause necrotic ulcerationsof various sizes and dimensions. The current standard of carefor brown spider bites includes analgesics, ice, compression,elevation, antihistamines, and surgical debridement. Hyperbaricoxygen therapy (HBOT) in the treatment of brown spider biteshas been administered in the early stage of ulceration, or …

Nonhealing Wounds Caused by Brown Spider Bites: Application of Hyperbaric Oxygen Therapy Read More »