Document Category: Dermatology

Brown Recluse Spider Envenomation: A Prospective Trial Hyperbaric Oxygen Therapy

Objectives: Loxosceles reclusa (brown recluse) spider bites can produce severe skin lesions that may neces sitate extensive surgical repair. This study delineated the effects of hyperbaric oxygen (HBO) therapy on these lesions by performing a prospective controlled animal study. Methods: After approval by the Institutional Animal Care and Use Committee, 41 New Zealand white rabbits received 64 intradermal …

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Comparison of Hyperbaric Oxygen and Dapsone Therapy for Loxosceles Envenomation

 Objective: To determine whether hyperbaric 0, (HBO), dapsone, or HBO plus dapsone affects lesion size in a swine model of Loxosceles envenomation. Methods: In a randomized controlled animal laboratory experiment, 32 piglets were assigned to 1 of 4 equal groups. Each piglet received 15 p,L of purified venom intradermally on day zero. Group 1 received no treatment; group 2 …

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HYPERBARKC OXYGEN EFFECTS ON BROWN RECLUSE SPIDER (LOXOSCELES RECLUSA) ENVENOMATION IN RABBITS

Hyperbaric oxygen effects on brown recluse spider (Loxosceles recluse) envenomation in rabbits. Toxicon 29, 989-996, 1991 .-Human loxoscelism was modeled in albino rabbits by injection of brown recluse spider (Loxosceles recluse) venom, and the effects of daily or twice-daily hyperbarkc oxygen treatment on wound healing were investigated . Lesions similar to those seen in humans …

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Hyperbaric oxygen preconditioning protects skin from UV-A damage

Abstract Hyperbaric oxygen therapy (HBOT) is used for anumber of applications, including the treatment of diabeticfoot ulcers and CO poisoning. However, we and others haveshown that HBOT can mobilize cellular antioxidantdefenses, suggesting that it may also be useful under cir cumstances in which tissue protection from oxidative dam age is desired. To test the protective …

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Hyperbaric Oxygen Therapy for the Treatment of Diabetic Foot Ulcers: A Health Technology Assessment

ABSTRACTBackgroundAbout 15% to 25% of people with diabetes will develop a foot ulcer. These wounds are often resistant to healing; therefore, people with diabetes experience lower limb amputation at about 20 times the rate of people without diabetes. If an ulcer does not heal with standard wound care, other therapeutic interventions are offered, one of …

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Adjunctive hyperbaric oxygen therapy in the treatment of thermal burns

A significant and consistently positive body of evi dence from animal and human studies of thermal injury support the use of hyperbaric oxygen as a means of preventing dermal ischemia, reducing edema, modulating the zone of stasis, preventing partial- to full-thickness conversion, preserving cel lular metabolism and promoting of healing. The vast majority of clinical …

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Livedoid vasculopathy managed with hyperbaric oxygen therapy

Livedoid vasculopathy is an uncommon condition resulting in painful lower extremity ulceration and scarring. This condition presents as purpuric macules and papules that progress to painful, irregular ulcers of the lower legs and dorsal feet. These ulcerations are often recurrent and chronic with spontaneous remissions and exacerbations that may be seasonal. The first case, a …

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Oxígeno hiperbárico, una alternativa terapéutica novedosa en la vasculopatía livedoide

Paciente femenina de 16 años de edad, natural de Cartagena, procedente de Bogotá, sin antecedentes previos conocidos, consulto´ por un cuadro clínico de 2 años de evolución consistente en la aparición de lesiones dolorosas en ambos miembros inferiores con ulceración, cambios de coloración en la piel de ambas extremidades e importante limitación para la marcha. …

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Livedoid vasculopathy: long-term follow-up results following hyperbaric oxygen therapy

Background: Livedoid vasculopathy, also known as atrophie blanche, is a recurrent painful vasculopathy appearing mostly on the lower limbs. Treatment is challenging and relapses are frequent. Objectives: To analyse the long-term effect and safety of hyperbaric oxygen (HBO) therapy in treating livedoid vasculopathy. Methods: Twelve patients with active livedoid vasculopathy were included in this study. All patients underwent …

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Vasculopatía livedoide: a propósito de un caso – Livedoid vasculopathy: regarding a case report

La vasculopatía livedoide es una enfermedad trombo-oclusiva no inflamatoria, rara, crónica y recurrente. Presenta características clínicas e histológicas distintivas, que la diferencian de las verdaderas vasculitis inflamatorias. Algunos casos se asocian con anormalidades en la coagulación o a otras enfermedades, principalmente autoinmunes. Presentamos el caso de una paciente, en la cual no se encontraron alteraciones …

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