Abstract: In hyperbaric oxygen therapy (HBOT), the subject is placed in a chamber containing 100%oxygen gas at a pressure of more than one atmosphere absolute. This treatment is used to hasten tissue recovery and improve its physiological aspects, by providing an increased supply of oxygen to the damaged tissue. In this review, we discuss the …
Abstract.Background: Previous studies have shown that hyperbaric oxygen therapy (HBOT) can improve the motor functions andmemory of post-stroke patients in the chronic stage.Objective: The aim of this study is to evaluate the effects of HBOT on overall cognitive functions of post-stroke patients inthe chronic stage. The nature, type and location of the stroke were investigated …
AbstractWe tested the hypothesis that if SPECT/CT-detected volumes of active and inactive parts of brain tissue present correlation with the results of hyperbaric oxygen therapy (HBOT) of ischemic stroke, SPECT imaging may serve as a selective tool for post-stroke patients to indicate cases that may significantly benefit from HBOT. A retrospective analysis was conducted on 62 consecutive patients administered …
Abstract: Stroke serves as a life-threatening disease and continues to face many challenges inthe development of safe and effective therapeutic options. The use of hyperbaric oxygen therapy(HBOT) demonstrates pre-clinical effectiveness for the treatment of acute ischemic stroke and reportsreductions in oxidative stress, inflammation, and neural apoptosis. These pathophysiological benefits contribute to improved functional recovery. Current …
An Extra Breath of Fresh Air: Hyperbaric Oxygenation as a Stroke Therapeutic Read More »
ABSTRACTObjective: Hyperbaric oxygen (HBO) is widely used in treating various neurological diseases. However,HBO for treatment of intracerebral haemorrhage (ICH) remains controversial, in either animal or clinicalstudies. Therefore, we conducted this systematic review and meta-analysis on studies describing theefficacy of HBO in animal models of ICH.Methods: Studies were identified by searching mainstream databases through November 2015. …
Controversy exists as to what transcutaneous oxygen(PICO.) levels are required for wound healing and what role hyperbaric oxygen has for this. Current information suggests that 30 to 40 mmHg juxta-wound oxygen tensions in room air are required. We recorded P,cO. measurements in room air and with hyperbaric oxygen in 190 patients with foot wounds; then …
Purpose This study was designed to investigate the possibleeffects of acute hyperbaric hyperoxia on respiratorymechanics of anaesthetised, positive-pressure ventilatedrats.Methods We measured respiratory mechanics by the endinflationocclusion method in nine rats previously acutelyexposed to hyperbaric hyperoxia in a standard fashion. Themethod allows the measurements of respiratory systemelastance and of both the ‘‘ohmic’’ and of the viscoelasticcomponents …
Background: Oxygen toxicity is one potential side effect of hyperbaric oxygen therapy (HBOT). Previous smallstudies showed mild reductions in pulmonary functions reflecting reductions in small airway conductance afterrepetitive hyperbaric oxygen sessions. However, there are no updated data with well performed pulmonary teststhat address the pulmonary effect of the currently used HBOT protocols.The aim of this …
Hyperbaric oxygen therapy effects on pulmonary functions: a prospective cohort study Read More »
Background: Snakebites are a neglected threat to global human health with a high morbidity rate. The present study explored the efficacy of antivenom with hyperbaric oxygen (HBO) intervention on snakebites, which could provide the experimental basis for clinical adjuvant therapy.Methods: Male Sprague–Dawley rats (n = 96) were randomized into four groups: the poison model was …
A patient suffered from an envenomation that, at his hospitalization, was judged severe: Grade 3 out of 3, as defined in clinical studies for CroFab™ antidote [Crotalidae Polyvalent Immune Fab (Ovine)]. In addition to the usual antivenom treatment we applied adjunctive hyperbaric oxygen (HBO2) therapy. Our aim was to facilitate better control of the lesions, already presenting as problematic wounds and …
HBO2 in snake envenomation (atrox albinus rattlesnake): a case report in a human Read More »
