Diabetic foot ulcer is a common chronic complication of diabetes mellitus. In addition to conventional primary ther apy, there are adjuvant therapy methods such as hyperbaric oxygen therapy for the healing of diabetic foot ulcer wounds. The present study aimed to determine the efficacy of hyperbaric oxygen therapy in diabetic foot ulcers based on Wagner …
AbstractBackground. Diabetic foot ulcer is one of the major complications of diabetes mellitus in adults.Objectives. The aim of the study was to conduct a planimetry evaluation of the effectiveness of hyperbaric oxygen therapy (HBOT) in the treatment of patients with vascular disorders caused by diabetic foot.Material and methods. The study included 94 patients, 30 females (32%) …
Background: Beneficial effects of hyperbaric oxygen on ischemic vasculardiseases have been noted. Acceleration of wound healing with basic fibroblast growth factor has also been reported. The authors employed combination therapy of hyperbaric oxygen and basic fibroblast growth factor in patients with skin ulcer in legs refractory to conventional therapy.Methods: Three men and four women were …
Animal experiments were performed to investigate whether and how the administration of hyperbaric oxygen (HBO) affects gene expressions ofprocollagens, matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in injured medial collateral ligament (MCL) and anterior cruciate ligament (ACL). In 64 Sprague-Dawley rats,the MCL of the left knee was lacerated at the midsubstance, and the …
Reyes T, Okerblom J, Ramirez-Sanchez I, Villarreal F, Patel HH,Bickler SW, Perdrizet GA, De Maio A. Early hyperbaric oxygentherapy improves survival in a model of severe sepsis. Am J PhysiolRegul Integr Comp Physiol 317: R160 –R168, 2019. First publishedMay 15, 2019; doi:10.1152/ajpregu.00083.2019.—Sepsis is a majorclinical challenge, with therapy limited to supportive interventions. There fore, the …
Early hyperbaric oxygen therapy improves survival in a model of severe sepsi Read More »
We present a case of rhino-orbitary mucormycosis which progressed despite liposomal amphotericin and early surgical debridement. Combined echinocandin and high dose liposomal amphotericin, repeated debridement, prolonged therapy with hyperbaric oxygen and continued therapy with posaconazole, along with strict diabetic control, allowed cure without disfigurement.
Abstract Purpose: Necrotising soft tissue infection (NSTI) is a deadly disease associated with a sig nificant risk of mortality and long term disability from limb and tissue loss. The aim of this study was to determine the effect of hyperbaric oxygen (HBO2) therapy on mortality, complication rate, discharge status/ location, hospital length of stay and …
SummaryIn a single-centre, retrospective, case-controlled study of patients attending the Alfred Hospital in Prahran, Victoria, we assessed the effect of hyperbaric oxygen therapy (HBOT) in reducing mortality or morbidity in patients with necrotising fasciitis (NF) over a 13-year period from 2002 to 2014. A total of three hundred and forty-one patients with NF were included in …
Necrotising soft tissue infections: the effect of hyperbaric oxygen on mortality Read More »
AbstractBackground: The utility of hyperbaric oxygen therapy (HBOT) in the treatment of necrotizing soft tissue in fections (NSTIs) has not been proved. Previous studies have been subject to substantial selection bias becauseHBOT is not available universally at all medical centers, and there is often considerable delay associated with itsinitiation. We examined the utility of HBOT …
Introduction: Necrotizing soft tissue infections (NSTI) are rare but potentially lethal disorders, and adequate management is time- and resource-demanding. This study aims to assess whether variations in the treatment modalities – surgery, hyper baric oxygen (HBO2)therapy and negative pressure wound therapy – had an impact on the length to definitive source control in NSTI patients …
