Hyperbaric oxygen has proven to be a useful treatment for chronic wounds. However, therapeutic conditions vary between treatment centers, and we wished to investigate the effects of different treatment pressures on cells under inflammatory conditions. Endothelial cells were exposed to a chronic wound model com prising hypoxia (2% O2 at 1 atmosphere absolute (atm abs); PO2 …
Oxygen is a prerequisite for successful wound healing due to the increased demand for reparative processes such as cell proliferation, bacterial defence, angiogenesis and collagen synthesis. Even though the role of oxygen in wound healing is not yet completely understood, many experimental and clinical obser vations have shown wound healing to be impaired under hypoxia. …
Oxygen in acute and chronic wound healing Read More »
Abstract Wound bed preparation is an organized approach to create an optimal environment for wound healing by the use of the most cost-effective therapeutic options. It has become an essential part of wound management and seeks to use the latest findings from molecular and cellular research to maximize the benefits of today’s advanced wound care …
Wounds have always afflicted humanity causing pain, suffering and death, and for thousands of years humans have tested and developed various techniques for their ability to induce wound healing. Hyperbaric oxygen therapy (HBOT) refers to placing a patient or their extremity in a chamber in which the pressure is raised several fold above ambient air pressure and the ambient …
Background: Oxygen is vital for healing wounds. It is intricately involved innumerous biological processes including cell proliferation, angiogenesis, andprotein synthesis, which are required for restoration of tissue function andintegrity. Adequate wound tissue oxygenation can trigger healing responsesand favorably influence the outcomes of other treatment modalities.The Problem: Chronic ischemic wounds fail to heal appropriately secondary toextreme …
Oxygen: Implications for Wound Healing Read More »
Abstract: Although many studies have shown that hyperbaric oxygen (HBO) therapy can signif icantly improve symptoms and quality of life of patients affected by femoral head necrosis, this therapy is not worldwide approved yet. This meta-analysis was performed to evaluate its clinical effect. Relevant studies published before May 2020 were systematically searched using terms related …
BackgroundThe aim of this study was to evaluate the biomechanics and structural bone matrix in dia betic rats subjected to hyperbaric oxygen therapy (HBO).MethodsTwenty-four male rats were divided into the following groups: Control; Control + HBO; Dia betic, and Diabetic + HBO. Diabetes was induced with streptozotocin (STZ) in the diabeticGroups. After 30 days, HBO …
AbstractBackground: To improve therapy for slow coronary flow (SCF), the effects of hyperbaric oxygen (HBO) therapy on vascular endothelial function in SCF patients is the focus of this investigation. Methods: Ninety-eight patients who exhibited chest discomfort were retrospectively analyzed, and di agnosed with SCF by coronary artery angiography at the Third Hospital of Hebei Medical University, Shijiazhuang, …
Aim: The role of hyperbaric oxygen therapy (HBOT) in the treatment of acute ischemic stroke is controversial. This study aims to investigate whether the peripheral insulin sensi tivity of type 2 diabetes patients suffering from intracerebral hemorrhage can be increased after HBOT.Methods: Fifty-two type 2 diabetes participants were recruited after being diagnosed with intracerebral hemorrhage in our …
AbstractIntrarenal hypoxia is an acknowledged factor contributing to the developmentof diabetic nephropathy. Hyperbaric oxygen (HBO) therapy is a well-knownadjuvant treatment for several medical conditions, such as decompressionsickness, infections, and wound healing. The underlying metabolic response ofHBO is largely unknown. In this study, we investigated the effect of HBO onthe intrarenal metabolic alteration in diabetes. Hyperpolarized …
Hyperbaric oxygen therapy reduces renal lactate production Read More »
