Document Category: Medical clinic

Hyperbaric oxygen: a novel modality to ameliorate experimental colitis

AbstractBackground—Hyperbaric oxygen (HBO) has been suggested to be beneficial ininflammatory bowel disease but the mechanisms responsible for its therapeu tic eVects have not been elucidated.Aim—To assess the eVect of HBO treat ment on colonic damage in two models ofexperimental colitis, and to examine whether this eVect is mediated by modula tion of NO synthesis.Methods—Colitis was …

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Systematic review: the safety and efficacy of hyperbaric oxygen therapy for inflammatory bowel disease

BackgroundHyperbaric oxygen therapy (HBOT) provides 100% oxygen under pressure,which increases tissue oxygen levels, relieves hypoxia and alters inflamma tory pathways. Although there is experience using HBOT in Crohn’s dis ease and ulcerative colitis, the safety and overall efficacy of HBOT ininflammatory bowel disease (IBD) is unknown.AimTo quantify the safety and efficacy of HBOT for Crohn’s …

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Hyperbaric oxygen treatment for inflammatory bowel disease: a systematic review and analysis

AbstractBackground: Traditionally, hyperbaric oxygen treatment (HBOT) has been used to treat a limited repertoire of disease, including decompression sickness and healing of problem wounds. However, some investigators haveused HBOT to treat inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis.Methods: Comprehensive searches were conducted in 8 scientific databases through 2011 to identify publications using …

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Hyperbaric Oxygen Therapy for Perineal Crohn’s Disease

Perineal lesions are a frequent and troublesome com plication of Crohn’s disease. Although there are various surgical and medical therapeutic regimens available totreat these lesions, all have significant associated mor bidity, mortality, and toxicity. Recently, the beneficial effects of hyperbaric oxygen therapy (HBOT) have been described in patients with severe or refractory perineal disease, but …

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Crohn’s disease and hyperbaric oxygen therapy1

ABSTRACTPURPOSE: Evaluate the application of Hyperbaric Oxygen Therapy (HBO) in patients with Crohn’s disease (CD) refractory topharmacologic therapy, who developed abdominal, anorectal or skin complications.METHODS: Fourteen selected patients with refractory CD and treated at the School of Medicine of Ribeirao Preto, University of SaoPaulo (FMRP-USP) and at the Center of Hyperbaric Medicine, São Paulo Hospital …

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Effects of acute hypoxia on auditory pathway of Wistar albino rats

Background/aim: Ischemia is insufficient blood flow to provide adequate oxygenation. In the present study, we aimed to show whether acute hypoxia has a critical oxygen value that may lead to the deterioration of cochlear function.Materials and methods: Under general anesthesia, prehypoxic signal-to-noise ratios were determined by distortion product otoacoustic emissions (DPOAE). The oxygen saturation (SaO2) values of …

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The use of hyperbaric oxygen therapy in acute hearing loss: a narrative review

AbstractIntroduction Acute hearing loss can have a major impact on a patient’s life. This holds true for both acute acoustic trauma (AAT) and idiopathic sudden sensorineural hearing loss (ISSHL), two devastating conditions for which no highly efective treatment options exist. This narrative review provides the rationale and evidence for HBOT in AAT and ISSHL.Methods Narrative review …

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Multivariate analysis of prognostic factors for idiopathic sudden sensorineural hearing loss treated with adjuvant hyperbaric oxygen therapy

Abstract The objective of this study is to evaluate possible prognostic factors of idiopathic sudden sensorineural hear ing loss (ISSNHL) treated with adjuvant hyperbaric oxygen therapy (HBOT) using univariate and multivariate analy ses. From January 2008 to October 2016, records of 178 ISSNHL patients treated with auxiliary hyperbaric oxygen therapy were reviewed to assess hearing recovery …

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Hyperbaric Oxygen Treatments Attenuate the Neutrophil-to-Lymphocyte Ratio in Patients with Idiopathic Sudden Sensorineural Hearing Loss

AbstractObjective. Hyperbaric oxygen therapy (HBOT) is a promising treatment in the management of idiopathic sudden sensori neural hearing loss (ISSNHL), but the specific mechanisms of HBOT in ISSNHL are still unclear. The curative effects ofHBOT in many diseases are related to the attenuation of inflammatory response. The neutrophil-to-lymphocyte ratio (NLR) is a new inflammatory marker …

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The Clinical Efficacy of Hyperbaric Oxygen Therapy in Idiopathic Sudden Sensorineural Hearing Loss and Tinnitus

AbstractBackground: Idiopathic Sudden Sensorineural Hearing Loss (ISSHL) affects about15,000 people annually worldwide and exceeds 30 db at 3 contiguous audiometricfrequencies. Thisstudy aims at evaluating the clinical efficacy of hyperbaric oxygentherapy (HBO2) in the management of ISSHL.Material and Methods: Fifty six patients were enrolled in the study suffering fromISSHL and tinnitus. The research protocol consisted of …

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