Abstract: Objective: To investigate the mechanism underlying the effect of hyperbaric oxygen (HBO) on hypoxic / ischemic brain damage (HIBD) in a neonatal rat model. Methods: A total of 30 neonatal SD rats aged 7 days were randomly assigned into control group, HIBD group and HBO group (n=10 per group). Following HIBD modeling in neonatal …
AbstractAutism spectrum disorder (ASD) afects~2% of children in the United States. The etiology of ASD likely involves environ mental factors triggering physiological abnormalities in genetically sensitive individuals. One of these major physiological abnormalities is mitochondrial dysfunction, which may afect a signifcant subset of children with ASD. Here we systemati cally review the literature on human …
A comprehensive literature search was performed to collate evidence of mitochondrial dysfunction in autism spectrum disorders (ASDs) with two primary objectives. First, featuresof mitochondrial dysfunction in the general population of children with ASD were identified.Second, characteristics of mitochondrial dysfunction in children with ASD and concomitant mitochondrial disease (MD) were compared with published literature of two …
AbstractBackground: Several uncontrolled studies of hyperbaric treatment in children with autism have reported clinical improvements; however, this treatment has not been evaluated to date with acontrolled study. We performed a multicenter, randomized, double-blind, controlled trial to assess the efficacy of hyperbaric treatment in children with autism.Methods: 62 children with autism recruited from 6 centers, ages …
Abstract: In hyperbaric oxygen therapy (HBOT), the subject is placed in a chamber containing 100%oxygen gas at a pressure of more than one atmosphere absolute. This treatment is used to hasten tissue recovery and improve its physiological aspects, by providing an increased supply of oxygen to the damaged tissue. In this review, we discuss the …
ABSTRACTObjective: To observe the effects of hyperbaric oxygen (HBO2) therapy on the treatment of sleep disorders and its safety in children with cerebral palsy (CP).Methods: A total of 71 recruited children were divided into two groups based on age: group 1, aged between 2 and 4 years; and group 2, aged between 4 and 6 years. The …
Objective: The present study aimed to assess the effect of intensive rehabilitation combined with hyperbaric oxygen (HBO2) therapy on gross motor function in children with cerebral palsy (CP).Methods: We carried out an open, observational, platform-independent study in 150 children with cerebral palsy with follow-up over eight months to compare the effects of standard intensive rehabili …
Abstract.Background: Previous studies have shown that hyperbaric oxygen therapy (HBOT) can improve the motor functions andmemory of post-stroke patients in the chronic stage.Objective: The aim of this study is to evaluate the effects of HBOT on overall cognitive functions of post-stroke patients inthe chronic stage. The nature, type and location of the stroke were investigated …
AbstractWe tested the hypothesis that if SPECT/CT-detected volumes of active and inactive parts of brain tissue present correlation with the results of hyperbaric oxygen therapy (HBOT) of ischemic stroke, SPECT imaging may serve as a selective tool for post-stroke patients to indicate cases that may significantly benefit from HBOT. A retrospective analysis was conducted on 62 consecutive patients administered …
Abstract: Stroke serves as a life-threatening disease and continues to face many challenges inthe development of safe and effective therapeutic options. The use of hyperbaric oxygen therapy(HBOT) demonstrates pre-clinical effectiveness for the treatment of acute ischemic stroke and reportsreductions in oxidative stress, inflammation, and neural apoptosis. These pathophysiological benefits contribute to improved functional recovery. Current …
An Extra Breath of Fresh Air: Hyperbaric Oxygenation as a Stroke Therapeutic Read More »
