Document Category: Surgery and transplant

The role of hyperbaric oxygen therapy in the treatment of sternal wound infection

SummarySternal wound dehiscence and infection are major problems for patients and health care providers. A range of risk factors, including diabetes, obesity and internal thoracic artery harvest, has been implicated. Several pathophysiological mechanisms, which may account for the development of infection, have been proposed. There is a growing body of evidence which suggests that sternal …

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Hyperbaric oxygen therapy as additional treatment in deep sternal wound infections – a single center’s experience

AbstractIntroduction: Deep sternal wound infection (DSWI) is one of the most serious complications after cardiac surgery proce dures, observed in 5% of patients. Current standard medical therapy for DSWI includes antibiotics, surgical debridement, resuturing or negative pressure wound therapy (NPWT). Un fortunately, in some cases these methods are insufficient, and additional therapeutic options are needed. Aim: To …

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Hyperbaric Oxygen Therapy for Wound Dehiscence After Intraoral Bone Grafting in the Nonirradiated Patient: A Case Series

Purpose: In maxillofacial surgery, hyperbaric oxygen treatment is used almost exclusively as adjunctive therapy for osteoradionecrosis of the mandible in irradiated patients. It also is used to prevent the occur rence of osteoradionecrosis in the irradiated patient when dental surgery is indicated. Theoretically, hyper baric oxygen therapy should benefit the nonirradiated patient in maxillofacial surgery …

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Can hyperbaric oxygen be used to prevent deep infections in neuro-muscular scoliosis surgery?

AbstractBackground: The prevalence of postoperative wound infection in patients with neuromuscular scoliosis surgery is significantly higher than that in patients with other spinal surgery. Hyperbaric oxygen has been used as a supplement to treat postsurgical infections. Our aim was to determine beneficiary effects of hyperbaric oxygentreatment in terms of prevention of postoperative deep infection in …

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Effect of hyperbaric oxygen therapy on bone prefabrication in rats

Objectives: This experimental study aimed to create a prefabricated vascularized bone graft using the interconnected porous coralline hydroxyapatite ceramic by combining vascular bundle implantation, mesenchymal stem cells, and hyperbaric oxygen therapy (HBOT) administration in a rat model. Methods: Forty-five male Sprague-Dawley rats were divided into three groups, each containing 15 rats. The hydroxyapatite ceramics were …

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Role of Hyperbaric Oxygen Therapy in the Treatment of Postoperative Organ/Space Sternal Surgical Site Infections

AbstractBackground A prospective trial was designed to evaluatethe effect of hyperbaric oxygen (HBO) therapy on organ/space sternal surgical site infections (SSIs) following car diac surgery that requires sternotomy.Methods A total of 32 patients who developed postop erative organ/space sternal SSI were enrolled in this study from 1999 through 2005. All patients were offered HBOtherapy. Group …

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Hyperbaric oxygen therapy for pediatric “hypospadias cripple”devaluating the advantages regarding graft take

SummaryIntroductionHypospadias cripple patients pose a major surgical chal lenge with high complication rates attributed mainly to graft contraction. Hyperbaric oxygen therapy (HBOT) is an established treatment for compromised grafts and used extensively as a salvage therapy for compromised grafts and ischemic non-healing wounds.ObjectiveWe evaluated the graft-take rates in hypospadias cripple cases undergoing a staged tubularized …

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Effects of Hyperbaric Oxygen on Proliferation and Differentiation of Osteoblasts from Human Alveolar Bone

In view of the controversy of the clinical use of hyperbaric oxygen (HBO) treatment to stimulate fracture healing and bone regeneration, we have analysed the effects of daily exposure to HBO on the proliferation and differentiation of human osteoblasts in vitro. HBO stimulated proliferation when osteoblasts were cultured in 10% foetal calf serum (FCS), whereas …

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Hyperbaric Oxygen Therapy Enhanced Circulating Levels of Endothelial Progenitor Cells and Angiogenesis Biomarkers, Blood Flow, in Ischemic Areas in Patients with Peripheral Arterial Occlusive Disease

Abstract: Background: This study tested the hypothesis that hyperbaric oxygen (HBO) therapy enhanced the circulating levels of endothelial progenitor cells (EPCs), soluble angiogenesis factors, and blood flow in ischemic areas in patients with peripheral arterial occlusive disease(PAOD). Methods: In total, 57 consecutive patients with PAOD undergoing the HBO therapy (3 atmospheres (atm) for 2 h …

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Hyperbaric Oxygen, Vasculogenic Stem Cells, and Wound Healing

Significance: Oxidative stress is recognized as playing a role in stem cell mobilization from peripheral sites and also cell function. Recent Advances: This review focuses on the impact of hyperoxia on vasculogenic stem cells and elements of wound healing. Critical Issues: Components of the wound-healing process in which oxidative stress has a positive impact on …

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