Document Category: Wounds

Effect of Hyperoxia on Vascular Endothelial Growth Factor Levels in a Wound Model

Hypothesis: Hyperbaric oxygen (HBO) therapy increases vascular endothelial growth factor (VEGF) levels in wounds.Design: Wounds were monitored for oxygen delivery during HBO treatment, and wound fluids were analyzed for VEGF and lactate on days 2, 5, and 10 following wounding. Setting: Experimental animal model. Interventions: Rats were randomized to HBO therapy and control groups. The …

Effect of Hyperoxia on Vascular Endothelial Growth Factor Levels in a Wound Model Read More »

View

Livedoid vasculopathy: long-term follow-up results following hyperbaric oxygen therapy

Background Livedoid vasculopathy, also known as atrophie blanche, is a recurrentpainful vasculopathy appearing mostly on the lower limbs. Treatment is challeng ing and relapses are frequent.Objectives To analyse the long-term effect and safety of hyperbaric oxygen (HBO)therapy in treating livedoid vasculopathy.Methods Twelve patients with active livedoid vasculopathy were included in thisstudy. All patients underwent HBO …

Livedoid vasculopathy: long-term follow-up results following hyperbaric oxygen therapy Read More »

View

Hyperbaric oxygen therapy for nonhealing vasculitic ulcers

Background. Cutaneous nonhealing ulceration is a threatening manifestation ofvasculitis. Hyperbaric oxygen (HBO), frequently used as adjuvant therapy for patientswith ischaemic ulcers, exerts additional beneficial effects on the vascular inflammatoryresponse.Aim. To evaluate the effect of HBO on vasculitis-induced nonhealing skin ulcers.Methods. The study population comprised 35 patients aged ‡ 18 years with severe,nonhealing, vasculitis-induced ulcers that …

Hyperbaric oxygen therapy for nonhealing vasculitic ulcers Read More »

View

Hyperbaric oxygen therapy activates hypoxiainducible factor 1 (HIF-1), which contributes to improved wound healing in diabetic mice: HBO therapy activates HIF

Hyperbaric oxygen (HBO) therapy has been used as an adjunctive therapy for diabetic foot ulcers, although its mechanism of action is not completely understood. Recently, it has been shown that HBO mobilizes the endothelial progenitor cells (EPCs) from bone marrow that eventually will aggregate in the wound. However, the gathering of the EPCs in diabetic …

Hyperbaric oxygen therapy activates hypoxiainducible factor 1 (HIF-1), which contributes to improved wound healing in diabetic mice: HBO therapy activates HIF Read More »

View

TRATAMIENTO CON OXIGENACIÓN HIPERBÁRICA EN ONCOLOGÍA

ResumenLa terapia de oxigenación hiperbárica (TOHB) combate la hipoxia, factor predisponente para la resistencia a terapias oncológicas convencionales. Su uso como sensibilizador en terapias convencionales ha demostrado aumentar la efectividad de la radioterapia y disminuir la mortalidad en algunos tumores de cabeza y cuello y existe amplia evidencia de su uso en las lesiones radioinducidas. Más aún, …

TRATAMIENTO CON OXIGENACIÓN HIPERBÁRICA EN ONCOLOGÍA Read More »

View

Deep Frostbite Treated With Hyperbaric Oxygen and Thrombolytic Therapies

Abstract: The authors present a case of deep frostbite treated with both hyperbaric oxygen and thrombolytic therapies. Both of these therapies are experimental and have not yet achieved widespread clinical use. The patient described in this paper sustained frostbite after becoming intoxicated and falling unconscious in a snowy field. He was treated acutely for hypothermia and came into the authors’ care …

Deep Frostbite Treated With Hyperbaric Oxygen and Thrombolytic Therapies Read More »

View

Hyperbaric oxygen – its mechanisms and efficacy

Background:This paper outlines therapeutic mechanisms of hyperbaric oxygen therapy (HBO2) and reviews data on its efficacy for clinical problems seen by plastic and reconstructive surgeons.Methods: The information in this review was obtained from the peer-reviewed medical literature.Results: Principal mechanisms of HBO2 are based on intracellular generation of reactive species of oxygen and nitrogen. Reactive species …

Hyperbaric oxygen – its mechanisms and efficacy Read More »

View

Hyperbaric oxygen therapy for a refractory skin ulcer after radical mastectomy and radiation therapy: a case report

AbstractBackground: Radiation therapy is performed as an adjuvant therapy when indicated following surgical resectionof malignant tumors. However, radiation exposure induces acute or chronic dermatitis, depending on theradiation dose, interval, tissue volume, or irradiated area of the body. Radiation-induced skin ulcers andosteomyelitis of the underlying bone are intractable late-stage complications of radiation therapy, and oftenrequire reconstructive …

Hyperbaric oxygen therapy for a refractory skin ulcer after radical mastectomy and radiation therapy: a case report Read More »

View