Document Category: Wounds

Hyperbaric Oxygen Therapy and Quality of Life: A Systematic Review

AbstractObjective: Hyperbaric oxygen therapy (HBOT) involves breathing pure oxygen in a high-pressure chamber. HBOT is a well established treatment for several diseases, such as serious infections, chronic diabetic foot ulcer, radiation injury, and hidradenitissuppurativa. There are various troublesome diseases that decrease pleasure in life in patients. HBOT has excellent effects in improv ing QOL in …

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Cost and mortality data of a regional limb salvage and hyperbaric medicine program for Wagner Grade 3 or 4 diabetic foot ulcers

We obtained costs and mortality data in two retrospec tive cohorts totaling 159 patients who have diabetes mellitus and onset of a diabetic foot ulcer (DFU). Data were collected from 2005 to 2013, with a follow-up period through September 30, 2014. A total of 106 patients entered an evidence-based limb salvage protocol (LSP) for Wagner Grade …

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Cost-effectiveness and budget impact of adjunctive hyperbaric oxygen therapy for diabetic foot ulcers

Background: Hyperbaric oxygen therapy (HBOT) has been proposed as an adjunct tostandard methods of care for diabetic foot ulcers (DFU). Its use may decrease the risk ofinfection and lower extremity amputations (LEAs). As part of a Canadian assessment, weestimated the cost-effectiveness and budget impact of HBOT in this application.Methods: We developed a decision model comparing …

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Hyperbaric oxygen therapy improves the effect of keloid surgery and radiotherapy by reducing the recurrence rate*

Abstract: Objective: Keloids are exuberant cutaneous scars that form due to abnormal growth of fibrous tissue fol lowing an injury. The primary aim of this study was to assess the efficacy and mechanism of hyperbaric oxygen therapy (HBOT) to reduce the keloid recurrence rate after surgical excision and radiotherapy. Methods: (1) A total of 240 …

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Hyperbaric Oxygen Therapy for Wound Dehiscence After Intraoral Bone Grafting in the Nonirradiated Patient: A Case Series

Purpose: In maxillofacial surgery, hyperbaric oxygen treatment is used almost exclusively as adjunctive therapy for osteoradionecrosis of the mandible in irradiated patients. It also is used to prevent the occur rence of osteoradionecrosis in the irradiated patient when dental surgery is indicated. Theoretically, hyper baric oxygen therapy should benefit the nonirradiated patient in maxillofacial surgery …

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Effect of hyperbaric oxygen therapy on bone prefabrication in rats

Objectives: This experimental study aimed to create a prefabricated vascularized bone graft using the interconnected porous coralline hydroxyapatite ceramic by combining vascular bundle implantation, mesenchymal stem cells, and hyperbaric oxygen therapy (HBOT) administration in a rat model. Methods: Forty-five male Sprague-Dawley rats were divided into three groups, each containing 15 rats. The hydroxyapatite ceramics were …

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Effects of Hyperbaric Oxygen on Proliferation and Differentiation of Osteoblasts from Human Alveolar Bone

In view of the controversy of the clinical use of hyperbaric oxygen (HBO) treatment to stimulate fracture healing and bone regeneration, we have analysed the effects of daily exposure to HBO on the proliferation and differentiation of human osteoblasts in vitro. HBO stimulated proliferation when osteoblasts were cultured in 10% foetal calf serum (FCS), whereas …

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Patient Outcomes and Factors Associated with Healing in Calciphylaxis Patients Undergoing Adjunctive Hyperbaric Oxygen Therapy

Abstract Calcific uremic arteriolopathy, also known as calciphylaxis, is a rare syndrome of small vessel calcification of unknown etiology causing painful, violaceous skin lesions that progress to form chronic non-healing ulcers and gangrene. Hyperbaric oxygen therapy (HBOT) can be used as adjunctive therapy in the treatment of these ulcers. However, due to paucity of cases, …

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Hyperbaric Oxygen Therapy Enhanced Circulating Levels of Endothelial Progenitor Cells and Angiogenesis Biomarkers, Blood Flow, in Ischemic Areas in Patients with Peripheral Arterial Occlusive Disease

Abstract: Background: This study tested the hypothesis that hyperbaric oxygen (HBO) therapy enhanced the circulating levels of endothelial progenitor cells (EPCs), soluble angiogenesis factors, and blood flow in ischemic areas in patients with peripheral arterial occlusive disease(PAOD). Methods: In total, 57 consecutive patients with PAOD undergoing the HBO therapy (3 atmospheres (atm) for 2 h …

Hyperbaric Oxygen Therapy Enhanced Circulating Levels of Endothelial Progenitor Cells and Angiogenesis Biomarkers, Blood Flow, in Ischemic Areas in Patients with Peripheral Arterial Occlusive Disease Read More »

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