Document Category: Wounds

Effects of Hyperbaric Oxygen at 1.25 Atmospheres Absolute with Normal Air on Macrophage Number and Infiltration during Rat Skeletal Muscle Regeneration

Use of mild hyperbaric oxygen less than 2 atmospheres absolute (2026.54 hPa)with normal air is emerging as a common complementary treatment for severemuscle injury. Although hyperbaric oxygen at over 2 atmospheres absolute with100% O2 promotes healing of skeletal muscle injury, it is not clear whether mildhyperbaric oxygen is equally effective. The purpose of the present …

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Effects of hyperbaric oxygen on gene expressions of procollagen, matrix metalloproteinase and tissue inhibitor of metalloproteinase in injured medial collateral ligament and anterior cruciate ligament

Abstract Animal experiments were performed toinvestigate whether and how the administration ofhyperbaric oxygen (HBO) affects gene expressions ofprocollagens, matrix metalloproteinases (MMPs) andtissue inhibitors of metalloproteinases (TIMPs) in in jured medial collateral ligament (MCL) and anteriorcruciate ligament (ACL). In 64 Sprague-Dawley rats,the MCL of the left knee was lacerated at the mid substance, and the ACL …

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Hyperbaric Oxygen Therapy for the Treatment of Diabetic Foot Ulcers: A Health Technology Assessment

ABSTRACTBackgroundAbout 15% to 25% of people with diabetes will develop a foot ulcer. These wounds are often resistant to healing; therefore, people with diabetes experience lower limb amputation at about 20 times the rate of people without diabetes. If an ulcer does not heal with standard wound care, other therapeutic interventions are offered, one of …

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Adjunctive hyperbaric oxygen therapy in the treatment of thermal burns

A significant and consistently positive body of evi dence from animal and human studies of thermal injury support the use of hyperbaric oxygen as a means of preventing dermal ischemia, reducing edema, modulating the zone of stasis, preventing partial- to full-thickness conversion, preserving cel lular metabolism and promoting of healing. The vast majority of clinical …

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