Document Category: Cardiology

Baroreflex-mediated cardiovascular responsesto hyperbaric oxygen. J Appl Physiol 115: 819–828, 2013.First published July 3, 2013; doi:10.1152/japplphysiol.00625.2013.—The cardiovascular system responds to hyperbaric hyperoxia (HBO2)with vasoconstriction, hypertension, bradycardia, and reduced cardiacoutput (CO). We tested the hypothesis that these responses are linkedby a common mechanism—activation of the arterial baroreflex. Baroreflexfunction in HBO2 was assessed in anesthetized and consciousrats …

Baroreflex-mediated cardiovascular responses to hyperbaric oxygen Read More »

Arterial and pulmonaryarterial hemodynamics and oxygen delivery/extraction in normal humansexposed to hyperbaric air and oxygen. J Appl Physiol 107: 336–345, 2009.First published April 30, 2009; doi:10.1152/japplphysiol.91012.2008.—Divers and hyperbaric chamber attendants breathe hyperbaric air routinely. Hyperbaric oxygen (HBO2) is used therapeutically frequently. Although much is understood about the hemodynamic physiology and gas exchange effects during hyperbaric …

Arterial and pulmonary arterial hemodynamics and oxygen delivery/extraction in normal humans exposed to hyperbaric air and oxygen Read More »

The microcirculation is anatomical and consists of arterioles, capillaries, and venules that perform metabolic requirements and oxygen distribution to the tissues. During physiological or pathological stress, it balances between the oxygen delivery and the demand. This delicate balance can play an important role in the progression of critical illnessesand has a role in the development of …

Microcirculation and Hyperbaric Oxygen Treatment Read More »

The actions of oxygen in the body are extremely complex, and are also involved in various signalling pathways.Hyperbaric oxygen is known to contribute to the improvement of conditions where tissue circulation is suboptimal, and has considerable usage in different treatment protocols and experimental investigations. However, the precise mecha-nism by which hyperbaric oxygen changes the functioning …

Influence of Hyperbaric Oxygen on Blood Vessel Reactivity: Concept of Changes in Conducted Vasomotor Response Read More »

BACKGROUND: Hyperbaric oxygen decreases ischemia-reperfusion–induced neutrophil/intercellular adhesion molecule-1 adhesion by blocking CD18 polarization. The purpose of this study was to evaluate whether this hyperbaric oxygen effect is nitric oxide dependent and to determine whether nitric oxide synthase is required. METHODS: A gracilis muscle flap was raised in nine groups of male Wistar rats. Global ischemic injury was induced by clamping the gracilis muscle pedicle artery and vein for 4 hours. The hyperbaric oxygen treatment consisted …

Hyperbaric oxygen inhibits ischemia-reperfusion-induced neutrophil CD18 polarization by a nitric oxide mechanism Read More »