Abstract Purpose: Necrotising soft tissue infection (NSTI) is a deadly disease associated with a sig nificant risk of mortality and long term disability from limb and tissue loss. The aim of this study was to determine the effect of hyperbaric oxygen (HBO2) therapy on mortality, complication rate, discharge status/ location, hospital length of stay and …
SummaryIn a single-centre, retrospective, case-controlled study of patients attending the Alfred Hospital in Prahran, Victoria, we assessed the effect of hyperbaric oxygen therapy (HBOT) in reducing mortality or morbidity in patients with necrotising fasciitis (NF) over a 13-year period from 2002 to 2014. A total of three hundred and forty-one patients with NF were included in …
Necrotising soft tissue infections: the effect of hyperbaric oxygen on mortality Read More »
AbstractBackground: The utility of hyperbaric oxygen therapy (HBOT) in the treatment of necrotizing soft tissue in fections (NSTIs) has not been proved. Previous studies have been subject to substantial selection bias becauseHBOT is not available universally at all medical centers, and there is often considerable delay associated with itsinitiation. We examined the utility of HBOT …
Hyperbaric oxygen has proven to be a useful treatment for chronic wounds. However, therapeutic conditions vary between treatment centers, and we wished to investigate the effects of different treatment pressures on cells under inflammatory conditions. Endothelial cells were exposed to a chronic wound model com prising hypoxia (2% O2 at 1 atmosphere absolute (atm abs); PO2 …
Oxygen is a prerequisite for successful wound healing due to the increased demand for reparative processes such as cell proliferation, bacterial defence, angiogenesis and collagen synthesis. Even though the role of oxygen in wound healing is not yet completely understood, many experimental and clinical obser vations have shown wound healing to be impaired under hypoxia. …
Oxygen in acute and chronic wound healing Read More »
Abstract Wound bed preparation is an organized approach to create an optimal environment for wound healing by the use of the most cost-effective therapeutic options. It has become an essential part of wound management and seeks to use the latest findings from molecular and cellular research to maximize the benefits of today’s advanced wound care …
Wounds have always afflicted humanity causing pain, suffering and death, and for thousands of years humans have tested and developed various techniques for their ability to induce wound healing. Hyperbaric oxygen therapy (HBOT) refers to placing a patient or their extremity in a chamber in which the pressure is raised several fold above ambient air pressure and the ambient …
ntroduction: This study examines patient reported outcome measures of women undergoing hyperbaric oxygentreatment (HBOT) after breast-conserving therapy.Method: Included were 57 women treated with HBOT for late radiation-induced tissue toxicity (LRITT) referred inthe period January 2014-December 2015. HBOT consisted of (on average) 47 sessions. In total, 80 min of 100 % O2was administered under increased pressure …
Purpose: Comparison of quality of life (QoL) and side effects in a randomized trial for early hyperbaric oxygen therapy (HBOT) after radiotherapy (RT).Methods and Materials: From 2006, 19 patients with tumor originating from the tonsillar fossa and/or soft palate(15), base of tongue (1), and nasopharynx (3) were randomized to receive HBOT or not. HBOT consisted …
Radiotherapy is a widely recognised treatment fornon-melanoma skin cancer. We report three casesof radiation-induced skin ulcers in which hyperbaricoxygen therapy was administered in 90-min ses sions, 5 days a week at 2.4 absolute atmospheres ina multiplace hyperbaric chamber. Hyperbaric oxy gen therapy is an outpatient treatment that does notdisplace other classical treatments and may be …
