Document Category: Oncology

Hyperbaric Oxygen Therapy and Quality of Life: A Systematic Review

AbstractObjective: Hyperbaric oxygen therapy (HBOT) involves breathing pure oxygen in a high-pressure chamber. HBOT is a well established treatment for several diseases, such as serious infections, chronic diabetic foot ulcer, radiation injury, and hidradenitissuppurativa. There are various troublesome diseases that decrease pleasure in life in patients. HBOT has excellent effects in improv ing QOL in …

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Hyperbaric oxygen therapy accelerates osteoblast differentiation and promotes bone formation

Objectives: Hyperbaric oxygen therapy (HBO) has been used as an adjunctive therapy in the treatment of radiotherapy or bisphosphonate-induced osteonecrosis of the jaw however the effect of HBO on osteoblast formation and mineralisation has not been extensively studied.The current study therefore examined the effects of HBO, elevated pressure or elevated oxygen alone on osteoblast differentiation …

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Hyperbaric oxygen therapy for chronic radiation-induced tissue injuries: Australasia’s largest study

AbstractAim: Chronic radiation injuries, although uncommon, are associated with poor quality of life in oncology patients. The present study assesses the efficacy and safety of hyperbaric oxygen therapy in the management of chronic radiation-induced tissue injuries.Methods: A retrospective analysis was performed in 276 consecutive patients treated with hyperbaric oxygen therapy for chronic radiation-induced tissue injuries …

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Hyperbaric oxygen therapy in the treatment of radio-induced lesions in normal tissues: a literature review

AbstractLate complications are one of the major factors limiting radiotherapy treatment, and their treatment is not codified. Hyperbaric oxygen(HBO) has been used in combination with radiotherapy for over half a century, either to maximise its effectiveness or in an attempt to treatlate complications. In this latter case, retrospective trials and case reports are prevailing in …

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TRATAMIENTO CON OXIGENACIÓN HIPERBÁRICA EN ONCOLOGÍA

ResumenLa terapia de oxigenación hiperbárica (TOHB) combate la hipoxia, factor predisponente para la resistencia a terapias oncológicas convencionales. Su uso como sensibilizador en terapias convencionales ha demostrado aumentar la efectividad de la radioterapia y disminuir la mortalidad en algunos tumores de cabeza y cuello y existe amplia evidencia de su uso en las lesiones radioinducidas. Más aún, …

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Hyperbaric oxygen therapy for late radiation-induced tissue toxicity: prospectively patient-reported outcome measures in breast cancer patients

ntroduction: This study examines patient reported outcome measures of women undergoing hyperbaric oxygentreatment (HBOT) after breast-conserving therapy.Method: Included were 57 women treated with HBOT for late radiation-induced tissue toxicity (LRITT) referred inthe period January 2014-December 2015. HBOT consisted of (on average) 47 sessions. In total, 80 min of 100 % O2was administered under increased pressure …

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EARLY HYPERBARIC OXYGEN THERAPY FOR REDUCING RADIOTHERAPY SIDE EFFECTS: EARLY RESULTS OF A RANDOMIZED TRIAL IN OROPHARYNGEAL AND NASOPHARYNGEAL CANCER

Purpose: Comparison of quality of life (QoL) and side effects in a randomized trial for early hyperbaric oxygen therapy (HBOT) after radiotherapy (RT).Methods and Materials: From 2006, 19 patients with tumor originating from the tonsillar fossa and/or soft palate(15), base of tongue (1), and nasopharynx (3) were randomized to receive HBOT or not. HBOT consisted …

EARLY HYPERBARIC OXYGEN THERAPY FOR REDUCING RADIOTHERAPY SIDE EFFECTS: EARLY RESULTS OF A RANDOMIZED TRIAL IN OROPHARYNGEAL AND NASOPHARYNGEAL CANCER Read More »

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HYPERBARIC OXYGEN TREATMENT OF CHRONIC REFRACTORY RADIATION PROCTITIS: A RANDOMIZED AND CONTROLLED DOUBLE-BLIND CROSSOVER TRIAL WITH LONG-TERM FOLLOW-UP

Purpose: Cancer patients who undergo radiotherapy remain at life-long risk of radiation-induced injury to normaltissues. We conducted a randomized, controlled, double-blind crossover trial with long-term follow-up to evaluatethe effectiveness of hyperbaric oxygen for refractory radiation proctitis.Methods and Materials: Patients with refractory radiation proctitis were randomized to hyperbaric oxygen at2.0 atmospheres absolute (Group 1) or air …

HYPERBARIC OXYGEN TREATMENT OF CHRONIC REFRACTORY RADIATION PROCTITIS: A RANDOMIZED AND CONTROLLED DOUBLE-BLIND CROSSOVER TRIAL WITH LONG-TERM FOLLOW-UP Read More »

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Does Hyperbaric Oxygen Administration Decrease Side Effect and Improve Quality of Life after Pelvic Radiation?

Aim: to evaluate the inuence of HBOT to the side effect and quality of life after pelvic radiation. Methods: this is an open randomized, parallel, prospective study conducted in Department of Obstetry and Gynecology, Oncology Division and Department of Radiotherapy. Endoscopy procedure was performed in Department of Internal Medicine and tissue biopsy in Department of Pathology Anatomy. The hyperbaric oxygen therapy (HBOT) was …

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Successful treatment of brain radiation necrosis resulting from triple-negative breast cancer with Endostar and short-term hyperbaric oxygen therapy: a case report

Abstract: Radiation necrosis (RN) is one of the complications of radiotherapy.Angiogenesis is a key factor underlying the development of RN, and Endostar, a safe and well-tolerated recombinant human endostatin, has been used to treat a variety of tumors.Thus far, however, no definitive reports on the use of Endostar for RN treatment have been reported. Here, …

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