AbstractAvascular necrosis of the femoral head is a progressive disease characterized by bone ischemia which evolves to subchondral collapse in more than 85% of patients. We describe a case of an early stage idiopathic avascular necrosis of the femoral head in a female patient that was characterized by bone marrow edema involving the whole femoral head and the majority of …
Background: Core decompression (CD) has been used in the treatment of pre-collapse stages avascular necrosis (AVN) with good results. Hyperbaric oygen therapy (HBO) was used as a non-invasive treatment for pre-collapse stages osteonecrosis with favorable results. This study aimed to compare the outcomes of HBO versus CD in stage II of non-traumatic AVN of the femoral head. Methods: Data …
ABSTRACTEarly stages of avascular necrosis of the femoral head (AVNFH) can be conservatively treated with hyperbaric oxygen therapy (HBOT). This study investigated how HBOT modulates inflammatory markers and reactive oxygen species (ROS) in patients with AVNFH. Twenty-three male patients were treated with two cycles of HBOT, 30 sessions each with a 30 days break between …
Hyperbaric oxygen therapy (HBOT) has beneficial effects on avascular necrosis of femoral head (ANFH), but its mechanism of action is still unclear. We investigated if HBOT upregulates serum osteoprotegerin (OPG) and/or inhibits osteoclast activation. 23 patients with unilateral ANFH at stage I, II and III consented to thestudy: the patients received standard HBOT. Serum OPG …
Hyperbaric oxygen therapy modulates serum OPG/RANKL in femoral head necrosis patients Read More »
Object. Hyperbaric oxygen therapy (HBO) is used as primary and/or adjunctive therapy in the treatment of vari ous clinical conditions complicated by local hypoxia. It may have therapeutic potential in the treatment of neurosur gical infections such as spinal osteomyelitis that are associated with significant morbidity rates. The purpose of this study was to evaluate …
Role of hyperbaric oxygen therapy in the treatment of bacterial spinal osteomyelitis Read More »
Abstract: Background and Objective: Pyogenic spinal infections are rare and potentially devastating, requiring prompt recognition and management. Parallel to the ever-increasing number of invasivespinal procedures, its incidence is on a steady rise, particularly in an expanding elderly population.The aim of this study was to evaluate the efficacy of hyperbaric oxygen (HBO2) therapy in the treatment …
Could Hyperbaric Oxygen Be a Solution in the Treatment of Spinal Infections? Read More »
Spinal cord injury (SCI) is a complex disease process that involves both primary and secondary mechanisms of injury and can leave patients with devastating functional impairment as well as psychological debilitation. While no curative treatment is available for spinal cord injury, current therapeutic approaches focus on reducing the secondary injury that follows SCI. Hyperbaric oxygen (HBO) therapy has …
Hyperbaric oxygen therapy of spinal cord injury Read More »
Abstract. The inflammatory response is an important source of secondary damage to neuronal tissue in the spinal cord following spinal cord injury (SCI). Hyperbaric oxygen (HBO) therapy reduces inflammation and promotes the restoration of locomotor function following SCI, however, the mechanisms underlying this effect remain to be determined. The aim of the current study was to investigate the mechanisms by which HBO …
Objective: To investigate the effect of BMSCs transplantation plus hyperbaric oxygen(HBO) on repair of rat SCI.Methods: Seventy five male rats were divided randomly into five groups: sham, vehicle,BMSCs transplantation group, combination group, 15 rats in each group. Every weekafter the SCI onset, all animals were evaluated for behavior outcome by Basso–Beattle–Bresnahan (BBB) score and inclined …
Abstract: Spinal cord injury (SCI) is a serious medical problem with high mortality and disability rates. Hyperbaric oxygen (HBO) treatment is beneficial for neurological recovery after SCI, but the underlying mechanisms await characterization. This study examined whether HBO treatment following SCI in rats exerts a neuroprotective effect through activation of the toll-like receptor (TLR) 2/nuclear factor (NF)-κB signaling …
