Document Category: Rehabilitation

Hyperbaric oxygen potentiates diabetic wound healing by promoting fibroblast cell proliferation and endothelial cell angiogenesis

Background: Diabetic foot ulcer (DFU), one of the diabetic complications, brings high burden to diabetic patients. Hyperbaric oxygen therapy (HBOT) has been proven to be an effective clinical method for the treatment of DFU. However, the mechanisms still to be elucidated.Methods: Diabetic foot mice model was established, and treated with hyperbaric oxygen. Haematoxylin & Eosin …

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Therapeutic Outcome of Hyperbaric Oxygen and Basic Fibroblast Growth Factor on Intractable Skin Ulcer in Legs: Preliminary Report

Background: Beneficial effects of hyperbaric oxygen on ischemic vasculardiseases have been noted. Acceleration of wound healing with basic fibroblast growth factor has also been reported. The authors employed combination therapy of hyperbaric oxygen and basic fibroblast growth factor in patients with skin ulcer in legs refractory to conventional therapy.Methods: Three men and four women were …

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Effects of hyperbaric oxygen on gene expressions of procollagen, matrix metalloproteinase and tissue inhibitor of metalloproteinase in injured medial collateral ligament and anterior cruciate ligament

Animal experiments were performed to investigate whether and how the administration of hyperbaric oxygen (HBO) affects gene expressions ofprocollagens, matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in injured medial collateral ligament (MCL) and anterior cruciate ligament (ACL). In 64 Sprague-Dawley rats,the MCL of the left knee was lacerated at the midsubstance, and the …

Effects of hyperbaric oxygen on gene expressions of procollagen, matrix metalloproteinase and tissue inhibitor of metalloproteinase in injured medial collateral ligament and anterior cruciate ligament Read More »

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Evidence-Supported HBO Therapy in Femoral Head Necrosis: A Systematic Review and Meta-Analysis

Abstract: Although many studies have shown that hyperbaric oxygen (HBO) therapy can signif icantly improve symptoms and quality of life of patients affected by femoral head necrosis, this therapy is not worldwide approved yet. This meta-analysis was performed to evaluate its clinical effect. Relevant studies published before May 2020 were systematically searched using terms related …

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Influence of hyperbaric oxygen on biomechanics and structural bone matrix in type 1 diabetes mellitus rats

BackgroundThe aim of this study was to evaluate the biomechanics and structural bone matrix in dia betic rats subjected to hyperbaric oxygen therapy (HBO).MethodsTwenty-four male rats were divided into the following groups: Control; Control + HBO; Dia betic, and Diabetic + HBO. Diabetes was induced with streptozotocin (STZ) in the diabeticGroups. After 30 days, HBO …

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Evaluation of a Hyperbaric Oxygen Therapy Intervention in Individuals with Fibromyalgia

AbstractObjective. To evaluate the feasibility and safety of hyperbaric oxygen therapy (HBOT) in patients with fibromyalgia (FM). Design. A cohort study with a delayed treatment arm used as a comparator. Setting. Hyperbaric Medicine Unit, Toronto General Hospital, Ontario, Canada. Subjects. Eighteen patients diagnosed with FM according tothe American College of Rheumatology and a score 60 …

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Comparative study of the effectiveness of a low-pressure hyperbaric oxygen treatment and physical exercise in women with fibromyalgia: randomized clinical trial

AbstractBackground: Fibromyalgia (FM) is characterized by chronic pain and fatigue, among other manifestations, thus advising interventions that do not aggravate these symptoms. The main  purpose of this study is to analyse the effect of low-pressure hyperbaric oxygen therapy (HBOT) on induced fatigue, pain, endurance and functional capacity, physical performance and cortical excitability when compared with a physical …

Comparative study of the effectiveness of a low-pressure hyperbaric oxygen treatment and physical exercise in women with fibromyalgia: randomized clinical trial Read More »

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Neuromuscular efficiency in fibromyalgia is improved by hyperbaric oxygen therapy: looking inside muscles by means of surface electromyography

ABSTRACTObjective. Neuromuscular efficiency (NME) is impaired in fibromyalgia (FM). Hyperbaric oxygen therapy (HBOT) is a medical treatment using 100% of oxy gen through an oxygen mask. HBOT in FM induces changes in cortical excita bility and a secondary reduction in pain and muscle fatigue. However, there are still no direct data indicating changes in muscle fatigue. …

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Strontium ranelate treatment in a postmenopausal woman with osteonecrosis of the jaw after long-term oral bisphosphonate administration: a case report

Abstract: Bisphosphonates (BPs) suppress bone resorption and increase bone strength, thus reducing the risk of fracture. Oral BPs are widely used for the prevention and treatment of osteoporosis and osteopenia. Here, we describe the case of a postmenopausal woman who took oral alendronate for .3 years for osteoporosis. The patient presented at the clinic with sharp jaw …

Strontium ranelate treatment in a postmenopausal woman with osteonecrosis of the jaw after long-term oral bisphosphonate administration: a case report Read More »

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