Document Category: Rehabilitation

Successful treatment of radiation-induced brain necrosis by hyperbaric oxygen therapy

We describe a 68-year-old man who underwent hyperbaric oxygen (HBO) therapy to manage radiation necrosis of the brain, whichdeveloped after two treatments with stereotactic radiosurgery (SRS) to the same lesion. The necrosis was subsequently treated with steroids alone for 2 months; however, he progressed clinically and radiographically. Improvement again was noted with the reinstitution of …

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Role of Hyperbaric Medicine for Osteoradionecrosis and Post Irradiation Wounds: an Institutional Experience

AbstractTo study the effectiveness of hyperbaric medicine in osteoradionecrosis and irradiation induced wounds. To evolve a protocol formanagement with combined surgical modality for irradiation induced injury. This study was carried out in the Plastic SurgeryDepartment, from November 2011 to December 2018. A total of 30 patients with post irradiation patients subjected to hyperbaricoxygen therapy during …

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Efficacy of Adjunctive Hyperbaric Oxygen Therapy in Osteoradionecrosis

AbstractOsteoradionecrosis (ORN) is a common consequence resulting from radiation in patients with cancer. Presently,hyperbaric oxygen therapy (HBOT) is proposed to have a role in improving wound healing in ORN patients. Thereis no strong scientific evidence to confirm the benefits of HBOT for treatment of ORN as an adjunctive treatment.This study aimed to determine the benefits …

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THE EFFICACY OF HYPERBARIC OXYGEN THERAPY IN THE TREATMENT OF RADIATION-INDUCED LATE SIDE EFFECTS

Purpose: We investigated the efficacy of hyperbaric oxygen therapy (HBOT) in the management of patients with radiation-induced late side effects, the majority of whom had failed previous interventions.Methods and Materials: Of 105 eligible subjects, 30 had either died or were not contactable, leaving 75 who qualified for inclusion in this retrospective study. Patients answered a …

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Transcutaneous Oxygen Measurements Under Hyperbaric Oxygen Conditions as a Predictor for Healing of Problem Wounds

Controversy exists as to what transcutaneous oxygen(PICO.) levels are required for wound healing and what role hyperbaric oxygen has for this. Current information suggests that 30 to 40 mmHg juxta-wound oxygen tensions in room air are required. We recorded P,cO. measurements in room air and with hyperbaric oxygen in 190 patients with foot wounds; then …

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A prospective, randomized clinical trial to compare the effect of hyperbaric to normobaric hyperoxia on cerebral metabolism, intracranial pressure, and oxygen toxicity in severe traumatic brain injury

Object. Oxygen delivered in supraphysiological amounts is currently under investigation as a therapy for severe traumatic brain injury (TBI). Hyperoxia can be delivered to the brain under normobaric as well as hyperbaricconditions. In this study the authors directly compare hyperbaric oxygen (HBO2) and normobaric hyperoxia (NBH)treatment effects.Methods. Sixty-nine patients who had sustained severe TBIs (mean …

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The Effect of Acute Exposure to Hyperbaric Oxygen on Respiratory System Mechanics in the Rat

Purpose This study was designed to investigate the possibleeffects of acute hyperbaric hyperoxia on respiratorymechanics of anaesthetised, positive-pressure ventilatedrats.Methods We measured respiratory mechanics by the endinflationocclusion method in nine rats previously acutelyexposed to hyperbaric hyperoxia in a standard fashion. Themethod allows the measurements of respiratory systemelastance and of both the ‘‘ohmic’’ and of the viscoelasticcomponents …

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How and why hyperbaric oxygen therapy can bring new hope for children suffering from cerebral palsy – An editorial perspective

Cerebral palsy (CP) is generally considered a non progressive condition resulting from neurological injury in the antenatal or perinatal period. The increased survival rates of premature infants due to advances in neonatal intensive care has led to increased incidence of CP, which is now higher than three in 1,000 births. Perinatal hypoxic-ischemic (HI) events resulting in …

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Hyperbaric Oxygenation Therapy in the Treatment of Cerebral Palsy: A Review and Comparison to Currently Accepted Therapies

ABSTRACTHyperbaric oxygenation therapy (HBOT) has shown promise inclinical trials and is sought by many parents of children withcerebral palsy (CP). There is unusual resistance to expanding theindications for this modality, which is the only treatment available forcertain conditions, such as decompression sickness and airembolism, and which is effective in a number of others related towound …

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Hyperbaric Oxygen Induces Late Neuroplasticity in Post Stroke Patients – Randomized, Prospective Trial

AbstractBackground: Recovery after stroke correlates with non-active (stunned) brain regions, which may persist for years. Thecurrent study aimed to evaluate whether increasing the level of dissolved oxygen by Hyperbaric Oxygen Therapy (HBOT)could activate neuroplasticity in patients with chronic neurologic deficiencies due to stroke.Methods and Findings: A prospective, randomized, controlled trial including 74 patients (15 were …

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