Document Category: Surgery and transplant

Hyperbaric Oxygen Therapy for the Compromised Graft or Flap

Significance: Tissue grafts and flaps are used to reconstruct wounds fromtrauma, chronic disease, tumor extirpation, burns, and infection. Despitecareful surgical planning and execution, reconstructive failure can occur dueto poor wound beds, radiation, random flap necrosis, vascular insufficiency, orischemia–reperfusion (IR). Traumatic avulsions and amputated compositetissues—compromised tissue—may fail from crush injury and excessivelylarge sizes. While never intended, …

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Therapeutic Outcome of Hyperbaric Oxygen and Basic Fibroblast Growth Factor on Intractable Skin Ulcer in Legs: Preliminary Report

Background: Beneficial effects of hyperbaric oxygen on ischemic vasculardiseases have been noted. Acceleration of wound healing with basic fibroblast growth factor has also been reported. The authors employed combination therapy of hyperbaric oxygen and basic fibroblast growth factor in patients with skin ulcer in legs refractory to conventional therapy.Methods: Three men and four women were …

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Necrotising soft tissue infections: the effect of hyperbaric oxygen on mortality

SummaryIn a single-centre, retrospective, case-controlled study of patients attending the Alfred Hospital in Prahran, Victoria, we assessed the effect of hyperbaric oxygen therapy (HBOT) in reducing mortality or morbidity in patients with necrotising fasciitis (NF) over a 13-year period from 2002 to 2014. A total of three hundred and forty-one patients with NF were included in …

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Hyperbaric oxygen treatment for inflammatory bowel disease: a systematic review and analysis

AbstractBackground: Traditionally, hyperbaric oxygen treatment (HBOT) has been used to treat a limited repertoire of disease, including decompression sickness and healing of problem wounds. However, some investigators haveused HBOT to treat inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis.Methods: Comprehensive searches were conducted in 8 scientific databases through 2011 to identify publications using …

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Role of Hyperbaric Medicine for Osteoradionecrosis and Post Irradiation Wounds: an Institutional Experience

AbstractTo study the effectiveness of hyperbaric medicine in osteoradionecrosis and irradiation induced wounds. To evolve a protocol formanagement with combined surgical modality for irradiation induced injury. This study was carried out in the Plastic SurgeryDepartment, from November 2011 to December 2018. A total of 30 patients with post irradiation patients subjected to hyperbaricoxygen therapy during …

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Efficacy of Adjunctive Hyperbaric Oxygen Therapy in Osteoradionecrosis

AbstractOsteoradionecrosis (ORN) is a common consequence resulting from radiation in patients with cancer. Presently,hyperbaric oxygen therapy (HBOT) is proposed to have a role in improving wound healing in ORN patients. Thereis no strong scientific evidence to confirm the benefits of HBOT for treatment of ORN as an adjunctive treatment.This study aimed to determine the benefits …

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Hyperbaric oxygen therapy for late radiation tissue injury

BackgroundCancer is a significant global health problem. Radiotherapy is a treatment for many cancers and about 50% of people having radiotherapywill be long-term survivors. Some will experience late radiation tissue injury (LRTI) developing months or years later. Hyperbaric oxygentherapy (HBOT) has been suggested as a treatment for LRTI based upon the ability to improve the …

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THE EFFICACY OF HYPERBARIC OXYGEN THERAPY IN THE TREATMENT OF RADIATION-INDUCED LATE SIDE EFFECTS

Purpose: We investigated the efficacy of hyperbaric oxygen therapy (HBOT) in the management of patients with radiation-induced late side effects, the majority of whom had failed previous interventions.Methods and Materials: Of 105 eligible subjects, 30 had either died or were not contactable, leaving 75 who qualified for inclusion in this retrospective study. Patients answered a …

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Adjunctive hyperbaric oxygen therapy in the treatment of thermal burns

A significant and consistently positive body of evi dence from animal and human studies of thermal injury support the use of hyperbaric oxygen as a means of preventing dermal ischemia, reducing edema, modulating the zone of stasis, preventing partial- to full-thickness conversion, preserving cel lular metabolism and promoting of healing. The vast majority of clinical …

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