Document Category: Medical clinic

Methemoglobinemia treated with hyperbaric oxygen therapy: A case report

Methemoglobinemia is a rare but clinically important condition that should be considered among dif ferential diagnosis’ in cyanosis. The conventional treatments of methemoglobinemia are high flow ox ygen and methylene blue therapies.We present a 52-year-old male patient who admitted to emergency room with severe cyanosis and dyspnea after he was exposed to paint thinner and …

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A CASE OF METHEMOGLOBINEMIA SUCCESSFULLY TREATED WITH HYPERBARIC OXYGENATION MONOTHERAPY

Abstract—Background: Methylene blue is the first line therapy for methemoglobinemia, but it can be intermittently unavailable due to production issues.For this clinical scenario, alternative treatment options need to be explored. Hyperbaric oxygenation (HBO) is conventionally applied as an adjunctive therapy during the systemic administration of methylene blue.Currently, little is known regarding the effects of HBO …

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Utilization of Hyperbaric Oxygen Therapy and Induced Hypothermia After Hydrogen Sulfide Exposure

Hydrogen sulfide is a toxic gas produced as a byproduct of organic waste and many industrial processes. Hydrogen sulfide exposure symptoms may vary from mild (dizziness, headaches, nausea) to severe lactic acidosis via its inhibition of oxidative phosphorylation, leading to cardiac arrhythmias and death. Treatment is generally supportive. We report the case of a patient …

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Myocardial and lung injuries induced by hydrogen sulfide and the effectiveness of oxygen therapy in rats

Objective. To study myocardial and lung injuries initiated by hydrogen sulfide, and evaluate the role and effectiveness of normobaric and hyperbaric oxygen (HBO) treatment in rats. Methods. One hundred healthy male Wistar rats were randomly divided into five groups: A: Normal control group (no H2S); B: H2S-exposed group; C: H2Sþ33% oxygen treatment group; D: H2Sþ50% …

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Carbon monoxide and cyanide poisoning in the burned pregnant patient: an indication for hyperbaric oxygen therapy

AbstractCarbon monoxide (CO) is a small molecule poison released as a product of incomplete combustion. CO binds hemoglobin, reducing oxygen delivery. This effect is exacerbated in the burned pregnant patient by fetal hemoglobin that binds carbon monoxide 2.5–3 fold stronger than maternal hemoglobin. With no signature clinical symptom, diagnosis depends on patient injury history, elevated …

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Hyperbaric oxygen therapy or hydroxycobalamin attenuates surges in brain interstitial lactate and glucose; and hyperbaric oxygen improves respiratory status in cyanide-intoxicated rats

ABSTRACTCyanide (CN) intoxication inhibits cellular oxidative metabolism and may result in brain damage. Hydroxyco balamin (OHCob) is one among other antidotes that may be used following intoxication with CN. Hyperbaric oxygen (HBO2) is recommended when supportive measures or antidotes fail. However, the effect of hydroxyco balamin or HBO2 on brain lactate and glucose concentrations during …

Hyperbaric oxygen therapy or hydroxycobalamin attenuates surges in brain interstitial lactate and glucose; and hyperbaric oxygen improves respiratory status in cyanide-intoxicated rats Read More »

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Neurocognitive sequelae after carbon monoxide poisoning and hyperbaric oxygen therapy

Carbon monoxide (CO) has been the leading cause of poisoning mortality in many countries and hyperbaric oxygen (HBO) is a widely accepted treatment for CO poisoning. However, some patients with CO poisoning will still develop neurocognitive sequelae regardless of HBO therapy, which can persist since CO poisoning or be present days to weeks after a …

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Hyperbaric Oxygen Therapy Is Associated With Lower Short- and Long-Term Mortality in Patients With Carbon Monoxide Poisoning

BACKGROUND: To date, there has been no consensus about the effect of hyperbaric oxygen therapy (HBOT) on the mortality of patients with carbon monoxide poisoning (COP). This retrospective nationwide population-based cohort study from Taiwan was conducted to clarify this issue.METHODS: Using the Nationwide Poisoning Database, we identified 25,737 patients with COP diagnosed between 1999 and …

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