We hypothesized that tissue hyperoxia would enhance and hypoxia inhibit neovascularization in a wound model. Therefore, we used female Swiss-Webster mice to examine the influence of differential oxygen treat-ment on angiogenesis. One milliliter plugs of Matrigels, a mixture of matrix proteins that supports but does not itself elicit angiogenesis, were injected subcutaneously into the mice. …
Hyperoxia and angiogenesis Read More »
We present the case of a non-dialyzed patient with chronic kidney disease and biopsy-proven calciphylaxis who presented with painful cutaneous ulcers on both legs. The skin ulcers drastically improved within 6 months after the initiation of hemodialysis, aggressive wound care, the control of a mineral and bone disor der, and the administration of sodium thiosulfate …
treating disorders other than decompression sickness. Still, HBO2is a treatmentmodality that has gained recognition in certain situations of ischaemia reper fusion. However, not much is known about its eVect on the endothelial cells.Based on earlier studies, the hypothesis was that HBO2treatment stimulates therelease of brinolytic factors. The aim of the study was to investigate …
Hypothesis: Hyperbaric oxygen (HBO) therapy increases vascular endothelial growth factor (VEGF) levels in wounds.Design: Wounds were monitored for oxygen delivery during HBO treatment, and wound fluids were analyzed for VEGF and lactate on days 2, 5, and 10 following wounding. Setting: Experimental animal model. Interventions: Rats were randomized to HBO therapy and control groups. The …
Effect of Hyperoxia on Vascular Endothelial Growth Factor Levels in a Wound Model Read More »
ABSTRACTWe present a case of Raynaud’s disease with digital ulcers that was successfully treated withhyperbaric oxygen therapy. Hyperbaric oxygen therapy can be considered as a safe and usefuladjunct treatment for intractable digital ulcers in patients with Raynaud’s disease.
Hyperbaric oxygen therapy has been approved for primary or adjunctive care in 14 indications.A hyperbaric environment exists when a patient’s whole body is physically exposed to 100%oxygen and pressure that is greater than one atmosphere absolute. Hyperbaric oxygen therapy works through the ideal gas laws and is effective as an adjunctive therapy in the treatment …
The Role of Hyperbaric Oxygen Therapy in Crush Injuries Read More »
Abstract: Background and objectives: Complex limb wounds with multiple tissue involvement are commonly due to high energy trauma. Tissue damage is a dynamic entity and the exact extent of the injury is rarely instantly perceptible. Hence, reconstruction frequently involves a multi-stage procedure concluding with tissue replacement. Materials and Methods: A retrospective study was conducted between …
AbstractMutilated hand injuries are a profound challenge to the plastic surgeon, and suchinjuries often lead to limb loss and severe functional impairment. Hyperbaric oxygentherapy (HBOT) appears to counteract tissue hypoxia and stimulate acute woundhealing. This study was performed to evaluate the efficacy of HBOT as an adjunctivetherapy in patients with a mutilated hand injury. Between …
Is hyperbaric oxygen therapy indispensable for saving mutilated hand injuries Read More »
AbstractAim: Chronic radiation injuries, although uncommon, are associated with poor quality of life in oncology patients. The present study assesses the efficacy and safety of hyperbaric oxygen therapy in the management of chronic radiation-induced tissue injuries.Methods: A retrospective analysis was performed in 276 consecutive patients treated with hyperbaric oxygen therapy for chronic radiation-induced tissue injuries …
AbstractLate complications are one of the major factors limiting radiotherapy treatment, and their treatment is not codified. Hyperbaric oxygen(HBO) has been used in combination with radiotherapy for over half a century, either to maximise its effectiveness or in an attempt to treatlate complications. In this latter case, retrospective trials and case reports are prevailing in …
