Document Category: Medical clinic

TRATAMIENTO CON OXIGENACIÓN HIPERBÁRICA EN ONCOLOGÍA

ResumenLa terapia de oxigenación hiperbárica (TOHB) combate la hipoxia, factor predisponente para la resistencia a terapias oncológicas convencionales. Su uso como sensibilizador en terapias convencionales ha demostrado aumentar la efectividad de la radioterapia y disminuir la mortalidad en algunos tumores de cabeza y cuello y existe amplia evidencia de su uso en las lesiones radioinducidas. Más aún, …

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Deep Frostbite Treated With Hyperbaric Oxygen and Thrombolytic Therapies

Abstract: The authors present a case of deep frostbite treated with both hyperbaric oxygen and thrombolytic therapies. Both of these therapies are experimental and have not yet achieved widespread clinical use. The patient described in this paper sustained frostbite after becoming intoxicated and falling unconscious in a snowy field. He was treated acutely for hypothermia and came into the authors’ care …

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Oxidative stress is fundamental to hyperbaric oxygen therapy

THERAPEUTIC MECHANISMS OF action for hyperbaric oxygen(HBO2) are based on elevation of both the partial pressure ofoxygen and hydrostatic pressure. Elevating the hydrostaticpressure increases partial pressure of gases and causes a reductionin the volume of gas-filled spaces according to Boyle’slaw. These actions have direct relevance to treating pathologicalconditions in which gas bubbles are present in …

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Hyperbaric Oxygen Therapy for the Compromised Graft or Flap

Significance: Tissue grafts and flaps are used to reconstruct wounds fromtrauma, chronic disease, tumor extirpation, burns, and infection. Despitecareful surgical planning and execution, reconstructive failure can occur dueto poor wound beds, radiation, random flap necrosis, vascular insufficiency, orischemia–reperfusion (IR). Traumatic avulsions and amputated compositetissues—compromised tissue—may fail from crush injury and excessivelylarge sizes. While never intended, …

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Hyperbaric oxygen therapy for chronic wounds (Review)

BackgroundChronic wounds are common and present a health problem with significant effect on quality of life. Various pathologies may causetissue breakdown, including poor blood supply resulting in inadequate oxygenation of the wound bed. Hyperbaric oxygen therapy(HBOT) has been suggested to improve oxygen supply to wounds and therefore improve their healing.ObjectivesTo assess the benefits and harms …

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Evaluation of the Occlusive Arterial Disease and Diabetic Angiopathy Treatment Effects by Hyperbaric Oxygenation

Introduction: One of the most severe complications of atherosclerosis is arterial occlusive disease (AOD) and with diabetic angiopathy (DA), is a common chronic problem in clinical practice worldwide. Hyperbaric oxygen (HBO) therapy is a therapeutic modality for solving all forms of hypoxia. Aim: To compare the treatment with HBO therapy in patients with AOD and DA ischemic …

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Transcutaneous Oxygen Measurements Under Hyperbaric Oxygen Conditions as a Predictor for Healing of Problem Wounds

Controversy exists as to what transcutaneous oxygen (PICO.) levels are required for wound healing and what role hyperbaric oxygen has for this. Current information sug gests that 30 to 40 mmHg juxta-wound oxygen tensions in room air are required. We recorded P,cO. measure ments in room air and with hyperbaric oxygen in 190 patients with …

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Systematic Review or Meta-analysis Systematic review and meta-analysis of clinical trials examining the effect of hyperbaric oxygen therapy in people with diabetes-related lower limb ulcers

AbstractAim To examine the efficacy of hyperbaric oxygen therapy in healing diabetes-related lower limb ulcers through a meta-analysis of randomized clinical trials.Methods A literature search was conducted to identify appropriate clinical trials. Inclusion required randomized study design and reporting of the proportion of diabetes-related lower limb ulcers that healed. A meta-analysis was performed to examine …

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Hyperbaric oxygen potentiates diabetic wound healing by promoting fibroblast cell proliferation and endothelial cell angiogenesis

Background: Diabetic foot ulcer (DFU), one of the diabetic complications, brings high burden to diabetic patients. Hyperbaric oxygen therapy (HBOT) has been proven to be an effective clinical method for the treatment of DFU. However, the mechanisms still to be elucidated.Methods: Diabetic foot mice model was established, and treated with hyperbaric oxygen. Haematoxylin & Eosin …

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