Document Category: Oncology

Radiation-induced cystitis treated with hyperbaric oxygen therapy (RICH-ART): a randomised, controlled, phase 2–3 trial

Background Late radiation cystitis is an adverse effect of cancer treatment with radiotherapy in the pelvic region. Symptoms of late radiation cystitis can be assessed with the Expanded Prostate Index Composite Score (EPIC). Previous reports indicate that hyperbaric oxygen therapy reduces symptoms from late radiation cystitis, but the evidence is predominantly based on non-randomised and retrospective studies. …

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Hyberbaric oxygen as sole treatment for severe radiation – induced haemorrhagic cystitis

Purpose: To examine the safety and efficacy of hyperbaric oxygen as the primary and sole treatment for severe radiation-induced haemorrhagic cystitis.Materials and methods: Hyperbaric oxygen was prospectively applied as primary treat ment in 38 patients with severe radiation cystitis. Our primary endpoint was the in cidence of complete and partial response to treatment, while the secondary …

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Hyperbaric oxygen therapy for refractory radiation-induced hemorrhagic cystitis

Objectives: To analyze the efficacy of hyperbaric oxygen for the treatment ofradiation-induced hemorrhagic cystitis and to identify factors associated with successfultreatment.Methods: Clinical records from 176 patients with refractory radiation-inducedhemorrhagic cystitis treated at the Portuguese Navy Center for Underwater andHyperbaric Medicine, during a 15-year period, were retrospectively analyzed. Evolutionof macroscopic hematuria was used to analyze treatment …

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Hyperbaric Oxygen Therapy for Hemorrhagic Radiation Cystitis

Background: Hemorrhagic radiation cystitis (HRC) is a significant clinical problem that occurs after pelvic radiation therapy and is often refractory. Objectives: To evaluate the efficacy and safety of hyperbaric oxygen therapy (HBO) for HRC. Methods: Daily 90 minute sessions of HBO at 2 ATM 100% oxygen were given to 32 HRC patients with ASTRO grades 3-4 hematuria. Results: The …

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Hyperbaric Oxygen Therapy for Radiation Cystitis in Patients with Prostate Cancer: A Long-Term Follow-Up Study

Abstract Objective: To assess the safety and efficacy of hyperbaric oxygen (HBO) for treating radiation cystitis a long-term fol low-up study was done in patients with prostate cancer, the second most common malignancy in Japan. Patients and Methods: A total of 38 patients at an age of 68 8 8 years with radiation cystitis following irradiation of prostate cancer were treated …

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Role of Hyperbaric Medicine for Osteoradionecrosis and Post Irradiation Wounds: an Institutional Experience

AbstractTo study the effectiveness of hyperbaric medicine in osteoradionecrosis and irradiation induced wounds. To evolve a protocol formanagement with combined surgical modality for irradiation induced injury. This study was carried out in the Plastic SurgeryDepartment, from November 2011 to December 2018. A total of 30 patients with post irradiation patients subjected to hyperbaricoxygen therapy during …

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Efficacy of Adjunctive Hyperbaric Oxygen Therapy in Osteoradionecrosis

AbstractOsteoradionecrosis (ORN) is a common consequence resulting from radiation in patients with cancer. Presently,hyperbaric oxygen therapy (HBOT) is proposed to have a role in improving wound healing in ORN patients. Thereis no strong scientific evidence to confirm the benefits of HBOT for treatment of ORN as an adjunctive treatment.This study aimed to determine the benefits …

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Hyperbaric oxygen therapy for late radiation tissue injury

BackgroundCancer is a significant global health problem. Radiotherapy is a treatment for many cancers and about 50% of people having radiotherapywill be long-term survivors. Some will experience late radiation tissue injury (LRTI) developing months or years later. Hyperbaric oxygentherapy (HBOT) has been suggested as a treatment for LRTI based upon the ability to improve the …

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THE EFFICACY OF HYPERBARIC OXYGEN THERAPY IN THE TREATMENT OF RADIATION-INDUCED LATE SIDE EFFECTS

Purpose: We investigated the efficacy of hyperbaric oxygen therapy (HBOT) in the management of patients with radiation-induced late side effects, the majority of whom had failed previous interventions.Methods and Materials: Of 105 eligible subjects, 30 had either died or were not contactable, leaving 75 who qualified for inclusion in this retrospective study. Patients answered a …

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Systemic chemotherapy using paclitaxel and carboplatin plus regional hyperthermia and hyperbaric oxygen treatment for non-small cell lung cancer with multiple pulmonary metastases: Preliminary results

AbstractPurpose: The purpose of this retrospective case series was to evaluate the toxicity and efficacy of systemic chemotherapy usingpaclitaxel and carboplatin plus regional hyperthermia (HT) and hyperbaric oxygen treatment (HBO) for non-small-cell lungcancer (NSCLC).Materials and methods: Twenty-two patients with NSCLC with multiple pulmonary metastases intravenously receivedpaclitaxel (50 mg/m2), carboplatin (area under the curve of 1.0–1.5) …

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