Document Category: Oncology

Anti-inflammatory effects of hyperbaric oxygen on irradiated laryngeal tissues

AbstractIntroduction: To manage the complications of irradiation of head and neck tissue is a challengingissue for the otolaryngologist. Definitive treatment of these complications is still controversial.Recently, hyperbaric oxygen therapy is promising option for these complications.Objective: In this study, we used biochemical and histopathological methods to investigate theefficacy of hyperbaric oxygen against the inflammatory effects of …

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Successful hyperbaric oxygen therapy for laryngeal radionecrosis after chemoradiotherapy for mesopharyngeal cancer: case report and literature review

Abstract Laryngeal radionecrosis is one of the mosttroublesome late complications of radiotherapy, because it isfrequently resistant to treatment and laryngectomy is requiredin the worst case. Here, we report a case of laryngeal radio necrosis, successfully treated by use of hyperbaric oxygen(HBO) therapy, in which laryngectomy was avoided. A67-year-old male received radical chemoradiotherapy (CRT)for mesopharyngeal cancer, …

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TREATMENT OF LARYNGEAL RADIONECROSIS WITH HYPERBARIC OXYGEN THERAPY: A CASE REPORT

An 81-year-old male with early-stage laryngeal carcinoma had been treated with 60 Gy curative radiotherapy. He complained of a sore throat, foul odor in the mouth, progressive dyspnea, and fever2 months after the completion of radiotherapy. Direct laryngoscopy revealed narrowing of the glottis withdiffuse ulcerative necrotic tissue. Biopsies at multiple sites and pathology revealed intense …

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Successful treatment of radiation-induced brain necrosis by hyperbaric oxygen therapy

We describe a 68-year-old man who underwent hyperbaric oxygen (HBO) therapy to manage radiation necrosis of the brain, whichdeveloped after two treatments with stereotactic radiosurgery (SRS) to the same lesion. The necrosis was subsequently treated with steroids alone for 2 months; however, he progressed clinically and radiographically. Improvement again was noted with the reinstitution of …

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Hyperbaric oxygen therapy: An alternative treatment for radiation-induced cutaneous ulcers

Radiotherapy is a widely recognised treatment fornon-melanoma skin cancer. We report three casesof radiation-induced skin ulcers in which hyperbaricoxygen therapy was administered in 90-min ses sions, 5 days a week at 2.4 absolute atmospheres ina multiplace hyperbaric chamber. Hyperbaric oxy gen therapy is an outpatient treatment that does notdisplace other classical treatments and may be …

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Hyperbaric oxygen therapy for a refractory skin ulcer after radical mastectomy and radiation therapy: a case report

Background: Radiation therapy is performed as an adjuvant therapy when indicated following surgical resectionof malignant tumors. However, radiation exposure induces acute or chronic dermatitis, depending on theradiation dose, interval, tissue volume, or irradiated area of the body. Radiation-induced skin ulcers andosteomyelitis of the underlying bone are intractable late-stage complications of radiation therapy, and oftenrequire reconstructive …

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Hyperbaric oxygen therapy for late radiation-induced tissue toxicity: prospectively patient-reported outcome measures in breast cancer patients

Introduction: This study examines patient reported outcome measures of women undergoing hyperbaric oxygentreatment (HBOT) after breast-conserving therapy.Method: Included were 57 women treated with HBOT for late radiation-induced tissue toxicity (LRITT) referred inthe period January 2014-December 2015. HBOT consisted of (on average) 47 sessions. In total, 80 min of 100 % O2was administered under increased pressure …

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Hyperbaric oxygen therapy in the treatment of radio-induced lesions in normal tissues: a literature review

AbstractLate complications are one of the major factors limiting radiotherapy treatment, and their treatment is not codified. Hyperbaric oxygen(HBO) has been used in combination with radiotherapy for over half a century, either to maximise its effectiveness or in an attempt to treatlate complications. In this latter case, retrospective trials and case reports are prevailing in …

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HYPERBARIC OXYGEN THERAPY FOR LATE SEQUELAE IN WOME

Purpose: Persisting symptomatology after breast-conserving surgery and radiation is frequently reported. Inmost cases, symptoms in the breast resolve without further treatment. In some instances, however, pain,erythema, and edema can persist for years and can impact the patient’s quality of life. Hyperbaric oxygentherapy was shown to be effective as treatment for late radiation sequelae. The objective …

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Hyperbaric oxygen therapy for radiation cystitis after pelvic radiotherapy: Systematic review of the recent literature

Abstract: The present study assessed the efficacy of hyperbaric oxygen therapy in reducing symptoms of radiation cystitis, a specific type of iatrogenic injury to the bladder, by systematic review of recent literature. The MEDLINE, Embase and Web of Science databases were searched using combinations of the terms “radiation,” “cystitis” and “hyperbaric oxygen” to identify articles …

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